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  • WCLC 2013

    15th World Conference on Lung Cancer

    Access to all presentations that occurred during the 15th World Conference on Lung Cancer in Sydney, Australia.

    Presentation Date(s):  
    • October 27 - 30, 2013
    • Total Presentations: 2517

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    MO12 - Prognostic and Predictive Biomarkers III

    • Type: Mini Oral Abstract Session
    • Track: Medical Oncology
    • Presentations: 12
    • Moderators:B. Han
    • Coordinates: 10/29/2013, 10:30 - 12:00, Parkside Ballroom B, Level 1
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      MO12.01 - Novel Mechanisms of Sensitivity and Acquired Resistance to HSP90 inhibition by Ganetespib

      10:30 - 10:35  |  Author(s): S. Busacca

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      MO12.02 - Association between Gene Expression Profiles and Clinical Outcome of Pemetrexed-Based Treatment in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer: Exploratory Results from a Phase II Study

      10:35 - 10:40  |  Author(s): D. Fennell

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      MO12.03 - Biomarker analysis of a randomized, controlled, multicenter clinical trial comparing pemetrexed/cisplatin and gmcitabine/cisplatin as first-line treatment for advanced nonsquamous non-small cell lung cancer

      10:40 - 10:45  |  Author(s): L. Zhang

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      MO12.04 - Biomarker Analysis of NCIC Clinical Trials Group IND.196, a Phase I study of erlotinib plus foretinib in advanced pretreated non-small cell lung cancer patients

      10:45 - 10:50  |  Author(s): N. Leighl

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      MO12.05 - A new biomarker Heat shock protein 90 alpha as therapeutic monitor and predictor for lung cancer patients

      10:50 - 10:55  |  Author(s): Y. Shi

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      MO12.06 - DISCUSSANT

      10:55 - 11:10  |  Author(s): V. Papadimitrakopoulou

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      MO12.07 - The prevalence of MET expression by immunohistochemistry (IHC) in the MetLung (OAM4971g) trial: a randomized, placebo-controlled, phase III study with erlotinib + onartuzumab (MetMAb) vs erlotinib + placebo in patients with previously treated non-small cell lung cancer (NSCLC)

      11:10 - 11:15  |  Author(s): M.J. Edelman

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      MO12.08 - Hepatocyte growth factor (HGF) serum levels predict for outcome in patients with Small Cell Lung Carcinoma (SCLC)

      11:15 - 11:20  |  Author(s): I. González

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      MO12.09 - BIM deletion polymorphism in Asian and treatment outcome to chemotherapy in advanced non-small cell lung cancer

      11:20 - 11:25  |  Author(s): J. Lee

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      MO12.10 - Analysis of BIM Deletion polymorphism in Chinese Patients with NSCLC

      11:25 - 11:30  |  Author(s): J. Zhong

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      MO12.11 - The predictive role of common BIM deletion polymorphism and BIM expression on the EGFR-TKI therapy in never-smoking lung adenocarcinoma

      11:30 - 11:35  |  Author(s): J. Han

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      MO12.12 - DISCUSSANT

      11:35 - 11:50  |  Author(s): A. Adjei

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    MO13 - SCLC I

    • Type: Mini Oral Abstract Session
    • Track: Medical Oncology
    • Presentations: 11
    • Moderators:C.K. Liam
    • Coordinates: 10/29/2013, 10:30 - 12:00, Bayside 201 - 203, Level 2
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      MO13.01 - Disease control rate at 8 weeks predicts subsequent survival in platinum-treated extensive stage small cell lung cancer (ES-SCLC): a patient level analysis of SWOG trials

      10:30 - 10:35  |  Author(s): P. Lara

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      MO13.02 - Age as a prognostic factor in small cell lung cancer. A pooled analysis of randomized clinical trials from the Manchester lung cancer group (MLCG) and the UK Medical Research Council Clinical Trials Unit (MRC CTU).

      10:35 - 10:40  |  Author(s): P. Wheatley-Price

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      MO13.03 - Duration of Thoracic Radiotherapy with Concurrent Chemotherapy is Important for Outcome of Patients with Limited-Stage Small Cell Lung Cancer (L-SCLC)

      10:40 - 10:45  |  Author(s): R. Komaki

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      MO13.04 - A Phase II Trial of second line Pazopanib in Small Cell Lung Cancer (SCLC) patients: Preliminary results in patients with sensitive disease

      10:45 - 10:50  |  Author(s): A. Kotsakis

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      MO13.05 - DISCUSSANT

      10:50 - 11:05  |  Author(s): M. Millward

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      MO13.06 - Prophylactic Cranial Irradiation for patients with Small Cell Lung Cancer with 30 Gy in 10 fractions - analysis of efficacy and subset analysis of neurocognitive impairment.

      11:05 - 11:10  |  Author(s): S. Saha

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      MO13.07 - Survival of small cell lung cancer patients undergoing lung resection in England 1998-2009

      11:10 - 11:15  |  Author(s): M. Luchtenborg

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      MO13.08 - A pilot study of adjuvant chemotherapy with irinotecan and cisplatin for completely resected high grade pulmonary neuroendocrine carcinona (Large cell neuroendocrine carcinoma and small cell lung cancer)

      11:15 - 11:20  |  Author(s): H. Kenmotsu

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      MO13.09 - Small cell lung cancer in daily practice; SCOT registry (Small cell lung Cancer treatment and OuTcome)

      11:20 - 11:25  |  Author(s): P.E. Postmus

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      MO13.10 - Prospective Molecular Evaluation of Small Cell Lung Cancer (SCLC) Utilizing the Comprehensive Mutation Analysis Program at Memorial Sloan-Kettering Cancer Center (MSKCC)

      11:25 - 11:30  |  Author(s): M.C. Pietanza

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      MO13.11 - DISCUSSANT

      11:30 - 11:45  |  Author(s): M.M.E. O'Brien

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    MO14 - Mesothelioma II - Surgery and Multimodality

    • Type: Mini Oral Abstract Session
    • Track: Mesothelioma
    • Presentations: 12
    • Moderators:E. Lim
    • Coordinates: 10/29/2013, 10:30 - 12:00, Bayside Gallery B, Level 1
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      MO14.01 - The impact of macroscopic complete resection radical pleurectomy for mesothelioma on pulmonary function

      10:30 - 10:35  |  Author(s): J. Friedberg

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      MO14.02 - 16 Year Experience of Routine Laparoscopy and Selective Contralateral Thoracoscopic Staging for Malignant Pleural Mesothelioma

      10:35 - 10:40  |  Author(s): J. Friedberg

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      MO14.03 - Meta-analysis of extrapleural pneumonectomy versus radical pleurectomy for patients with resectable malignant pleural mesothelioma

      10:40 - 10:45  |  Author(s): D. Tian

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      MO14.04 - Current evidence of pleurectomy in the treatment of malignant pleural mesothelioma

      10:45 - 10:50  |  Author(s): C. Cao

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      MO14.05 - Intracavitary Cisplatin-Fibrin Chemotherapy after Resection for Malignant Pleural Mesothelioma Patients (INFLuenCe-Meso) - preliminary results

      10:50 - 10:55  |  Author(s): I. Opitz

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      MO14.06 - DISCUSSANT

      10:55 - 11:10  |  Author(s): B. McCaughan

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      MO14.07 - Elevated tumour expression of miR-210 is associated with short survival in malignant pleural mesothelioma patients undergoing extrapleural pneumonectomy

      11:10 - 11:15  |  Author(s): M.B. Kirschner

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      MO14.08 - Validation of a stage-independent pre-operative risk assessment algorithm for patients considering surgery for malignant pleural mesothelioma.

      11:15 - 11:20  |  Author(s): W. Richards

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      MO14.09 - 5-year experience with accelerated induction hypofractionated hemithoracic intensity modulated radiation therapy (IMRT) followed by extrapleural pneumonectomy (EPP) for malignant pleural mesothelioma (MPM)

      11:20 - 11:25  |  Author(s): M. De Perrot

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      MO14.11 - Safety of hemithoracic pleural intensity-modulated radiation therapy (IMRT) for malignant pleural mesothelioma (MPM) in the multimodality setting: interim analysis of a phase II study.

      11:25 - 11:30  |  Author(s): A.J. Wu

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      MO14.12 - Neoadjuvant Hemithoracic Intensity Modulated Radiotherapy: The "SMART" Approach for Managing Malignant Pleural Mesothelioma

      11:30 - 11:35  |  Author(s): J. Cho

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      MO14.13 - DISCUSSANT

      11:35 - 11:50  |  Author(s): M.M. Tin

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    O12 - Lung Cancer Biology II

    • Type: Oral Abstract Session
    • Track: Biology
    • Presentations: 8
    • Moderators:Y. Nakanishi
    • Coordinates: 10/29/2013, 10:30 - 12:00, Parkside 110 A+B, Level 1
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      O12.01 - Prospective isolation of human lung stem/progenitor cells and their role in the initiation of lung cancer

      10:30 - 10:40  |  Author(s): C.E. Weeden

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      O12.02 - Pathway Analysis of Gene Expression Profiles that Distinguish Persistent from Regressive Bronchial Dysplasia Indicate Synergistic Role for Polo-Like Kinase 1 (PLK1) and Epoxide Hydrolase 3 (EPHX3) in Malignant Progression.

      10:40 - 10:50  |  Author(s): D.T. Merrick

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      O12.03 - Pseudogenes as miRNA sponges in non-small cell lung cancer

      10:50 - 11:00  |  Author(s): G.L. Stewart

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      O12.04 - DISCUSSANT

      11:00 - 11:15  |  Author(s): K. Sutherland

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      O12.05 - Defining the role of ZEB1 in the pathogenesis of non-small cell lung cancer (NSCLC) using immortalized human bronchial epithelial cells (HBECs)

      11:15 - 11:25  |  Author(s): J.E. Larsen

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      O12.06 - Hedgehog/Gli Promotes Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer

      11:25 - 11:35  |  Author(s): H. Li

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      O12.07 - Pulmonary fibroblasts increase EMT signaling and decrease sensitivity to chemotherapy in non-small cell lung cancer cells via TGF-beta and IL-6 signaling

      11:35 - 11:45  |  Author(s): Y. Shintani

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      O12.08 - DISCUSSANT

      11:45 - 12:00  |  Author(s): J. Minna

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    O13 - Limited Resections

    • Type: Oral Abstract Session
    • Track: Surgery
    • Presentations: 8
    • Moderators:G.M. Wright
    • Coordinates: 10/29/2013, 10:30 - 12:00, Bayside 204 A+B, Level 2
    • +

      O13.01 - Limited Resection Trial for Pulmonary Ground-glass Opacity Nodules: Case Selection Based on High Resolution Computed Tomography: Interim Results

      10:30 - 10:40  |  Author(s): J. Yoshida

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      O13.02 - Is the Limited Surgical Resection Appropriate for Non-Small Cell Lung Cancers More than 2 cm in a Diameter? - Proposed Surgical Indication by the Presence of Ground-glass Opacity of The Tumor on Thin-section CT scan

      10:40 - 10:50  |  Author(s): T. Maeyashiki

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      O13.03 - Survival of 1963 lobectomy-tolerable patients who underwent limited resection for cStage I non-small cell lung cancer

      10:50 - 11:00  |  Author(s): M. Yano

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      O13.04 - DISCUSSANT

      11:00 - 11:15  |  Author(s): H. Asamura

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      O13.05 - Outcomes of Sublobar Resection Versus Lobectomy for Non small cell Lung Cancer (NSCLC) with IPF

      11:15 - 11:25  |  Author(s): H.J. Sim

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      O13.06 - Vio-soft-coagulation for repair of air leak from dissected intersegmental plane during thoracoscopic segmentectomy

      11:25 - 11:35  |  Author(s): A. Watanabe

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      O13.07 - Preoperative Predictive Factors of Nodal Metastasis in Patients with cT1 Lung Cancer

      11:35 - 11:45  |  Author(s): L. Ren

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      O13.08 - DISCUSSANT

      11:45 - 12:00  |  Author(s): N. Alam

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    O14 - Radiotherapy - Toxicity and Clinical Trials

    • Type: Oral Abstract Session
    • Track: Radiation Oncology + Radiotherapy
    • Presentations: 8
    • Moderators:G. Pratt
    • Coordinates: 10/29/2013, 10:30 - 12:00, Parkside Ballroom A, Level 1
    • +

      O14.01 - Memory preservation with conformal avoidance of the hippocampus during whole-brain radiotherapy for patients with brain metastases: Preliminary results of RTOG 0933

      10:30 - 10:40  |  Author(s): V. Gondi

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      O14.02 - Vertebral fractures in NSCLC patients treated with IMRT and concurrent chemotherapy

      10:40 - 10:50  |  Author(s): W. Uyterlinde

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      O14.03 - Using generalized equivalent uniform dose (gEUD) to model volume effects for brachial plexopathy after high-dose stereotactic body radiation therapy (SBRT)

      10:50 - 11:00  |  Author(s): S.U. Din

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      O14.04 - DISCUSSANT

      11:00 - 11:15  |  Author(s): F. Mornex

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      O14.05 - Effect of Postoperative 3D-Conformal Radiotherapy (3DCRT) for Patients with pIIIA-N2 non-small-cell lung cancer (NSCLC) after Complete Resection and Adjuvant Chemotherapy: Interim Analysis of a Prospective Phase III Study

      11:15 - 11:25  |  Author(s): Z. Hui

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      O14.06 - Investigation of a Patient Reported Outcome (PRO) tool to assess radiotherapy-related toxicity in patients with lung cancer

      11:25 - 11:35  |  Author(s): M. Christodoulou

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      O14.07 - IDEAL CRT: Isotoxic Dose Escalation and Acceleration in Lung Cancer ChemoRadiotherapy - a phase I/II trial of concurrent chemoradiation with dose-escalated radiotherapy in patients with stage II or stage III Non-Small Cell Lung Cancer.

      11:35 - 11:45  |  Author(s): D.B. Landau

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      O14.08 - DISCUSSANT

      11:45 - 12:00  |  Author(s): S.K. Vinod

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    O15 - NSCLC - Chemotherapy II

    • Type: Oral Abstract Session
    • Track: Medical Oncology
    • Presentations: 8
    • Moderators:G. Richardson
    • Coordinates: 10/29/2013, 10:30 - 12:00, Bayside Auditorium A, Level 1
    • +

      O15.01 - Evaluation of a "watch and wait" approach for patients with newly diagnosed advanced non-small cell lung cancer in a diverse community population

      10:30 - 10:40  |  Author(s): K. Noonan

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      O15.02 - The Spanish Lung Cancer Group (SLCG) BRCA1-RAP80 Expression Customization (BREC) randomized phase III trial of customized chemotherapy in advanced non-small-cell lung cancer (NSCLC) patients with wild-type epidermal growth factor receptor (EGFR) (NCT00617656/GECP-BREC)

      10:40 - 10:50  |  Author(s): R. Rosell

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      O15.03 - Phase III, randomized, multicenter study comparing in elderly patients (≥70 years) with stage IV non small-cell lung cancer (NSCLC) a standard strategy of treatment allocation (carboplatin based bi-therapy or monotherapy with docetaxel) based on performance status (PS) and age with an experimental strategy allocating the same chemotherapies or best supportive care (BSC) according to a comprehensive geriatric assessment (CGA) - Study ESOGIA-GFPC-GECP 08-02.

      10:50 - 11:00  |  Author(s): R. Corre

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      O15.04 - DISCUSSANT

      11:00 - 11:15  |  Author(s): R. Lilenbaum

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      O15.05 - Randomized Phase III Trial of S-1 plus Cisplatin versus Docetaxel plus Cisplatin for Advanced Non-Small-Cell Lung Cancer (TCOG0701): Subgroup Analysis.

      11:15 - 11:25  |  Author(s): O. Ishimoto

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      O15.06 - Randomized Phase III Trial of Gemcitabine (G)/Carboplatin (C) with or without Iniparib (I) in Patients (Pts) with Previously Untreated Stage IV Squamous Lung Cancer

      11:25 - 11:35  |  Author(s): D. Spigel

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      O15.07 - Final results of CTONG 0806: a phase II trial comparing pemetrexed with gefitinib as second-line treatment of advanced non-squamous NSCLC patients with wild-type EGFR

      11:35 - 11:45  |  Author(s): Q. Zhou

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      O15.08 - DISCUSSANT

      11:45 - 12:00  |  Author(s): J.S. Lee

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    O16 - NSCLC - Targeted Therapies III

    • Type: Oral Abstract Session
    • Track: Medical Oncology
    • Presentations: 8
    • Moderators:H.A. Wakelee
    • Coordinates: 10/29/2013, 10:30 - 12:00, Parkside Auditorium, Level 1
    • +

      O16.01 - Impact of tumor burden on the overall survival analysis of the LUME-Lung 1 study: a randomized, double-blind phase 3 trial of nintedanib (BIBF 1120) + docetaxel in NSCLC patients progressing after first-line chemotherapy

      10:30 - 10:40  |  Author(s): M. Reck

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      O16.02 - Efficacy of standard care for second-line advanced non-small cell lung cancer (NSCLC) by KRAS mutation status: observations on MEK inhibitor enhancement of chemotherapy

      10:40 - 10:50  |  Author(s): P.A. Jänne

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      O16.03 - Cost-utility analysis of first-line treatment with erlotinib versus chemotherapy in EGFR-mutant advanced non-small-cell lung cancer (NSCLC): economic analysis of EURTAC trial

      10:50 - 11:00  |  Author(s): A. Vergnenegre

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      O16.04 - DISCUSSANT

      11:00 - 11:15  |  Author(s): J.C. Yang

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      O16.05 - Efficacy, safety, and patient-reported outcomes (PROs) with crizotinib versus chemotherapy in Asian patients in a phase III study of previously treated advanced ALK-positive non-small cell lung cancer (NSCLC)

      11:15 - 11:25  |  Author(s): M. Nishio

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      O16.06 - A phase 1 dose escalation study of a new ALK inhibitor, CH5424802/RO5424802, in ALK+ Non-Small Cell Lung Cancer (NSCLC) patients who have failed crizotinib (AF-002JG/NP28761, NCT01588028).

      11:25 - 11:35  |  Author(s): S. Gadgeel

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      O16.07 - Consistent therapeutic efficacy of CH5424802/RO5424802 in brain metastases among crizotinib-refractory ALK-positive non-small cell lung cancer (NSCLC) patients in an ongoing phase I/II study (AF-002JG/NP28761, NCT01588028).

      11:35 - 11:45  |  Author(s): S.I. Ou

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      O16.08 - DISCUSSANT

      11:45 - 12:00  |  Author(s): D..R. Camidge

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    O17 - Anatomical Pathology I

    • Type: Oral Abstract Session
    • Track: Pathology
    • Presentations: 8
    • Moderators:K. Jones
    • Coordinates: 10/29/2013, 10:30 - 12:00, Bayside 105, Level 1
    • +

      O17.01 - Prognostic and predictive value of a new IASLC/ATS/ERS lung adenocarcinoma classification in a pooled analysis of four adjuvant chemotherapy trials: a LACE-Bio study

      10:30 - 10:40  |  Author(s): E.M. Brambilla

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      O17.02 - Clinicopathologic, radiologic, and molecular characteristics of completely resected mucinous adenocarcinomas in the lung: Implications for prognosis

      10:40 - 10:50  |  Author(s): H.Y. Lee

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      O17.03 - Morphological and Mucin profile of lung adenocarcinoma harboring driver mutation

      10:50 - 11:00  |  Author(s): N. Motoi

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      O17.04 - DISCUSSANT

      11:00 - 11:15  |  Author(s): M.S. Tsao

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      O17.05 - Accuracy and Interobserver Agreement in Identifying Histologic Subtypes in Stage I Lung Adenocarcinomas ≤3 cm Using Frozen Section

      11:15 - 11:25  |  Author(s): Y. Yeh

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      O17.06 - Tumor Budding and Nuclear Grade, but not Histologic Subtype, Are Significant Prognostic Factors, Independent of TNM Stage, in Patients with Lung Squamous Cell Carcinoma

      11:25 - 11:35  |  Author(s): K. Kadota

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      O17.07 - Prevalence, morphology and natural history of FGFR1-amplified lung cancer detected by FISH and SISH

      11:35 - 11:45  |  Author(s): P.A. Russell

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      O17.08 - DISCUSSANT

      11:45 - 12:00  |  Author(s): W.A. Cooper

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    O18 - Cancer Control and Epidemiology II

    • Type: Oral Abstract Session
    • Track: Prevention & Epidemiology
    • Presentations: 8
    • Moderators:M.R. Spitz
    • Coordinates: 10/29/2013, 10:30 - 12:00, Bayside 103, Level 1
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      O18.01 - Multi-'omic analysis of an arsenic-associated lung squamous cell carcinoma reveals specific DNA level signatures

      10:30 - 10:40  |  Author(s): V.D. Martinez Zamora

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      O18.02 - Impacts of environmental tobacco smoke on EGFR mutations and ALK rearrangements in never smokers with non-small cell lung cancer: Analyses on a prospective multinational ETS registry

      10:40 - 10:50  |  Author(s): A. Kubo

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      O18.03 - The BioCAST / IFCT-1002 study: a comprehensive overview of demographic, risk exposure and somatic mutations of non-small cell lung cancer occurring among French never smokers

      10:50 - 11:00  |  Author(s): S. Couraud

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      O18.04 - Impact of Passive Smoking on molecular pattern in Never Smokers with Non-Small Cell Lung Cancer: Findings from the BioCAST / IFCT-1002 Study

      11:00 - 11:10  |  Author(s): S. Couraud

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      O18.05 - DISCUSSANT

      11:10 - 11:25  |  Author(s): P.P. Massion

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      O18.06 - Vietnamese non-small cell lung cancer patients in California: molecular profiles and clinical characteristics

      11:25 - 11:35  |  Author(s): K.H. Nguyen

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      O18.07 - A Retrospective Cohort Mortality Study in Jingchuan of china - the Largest Nickel Population in World

      11:35 - 11:45  |  Author(s): N. Cheng

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      O18.08 - DISCUSSANT

      11:45 - 12:00  |  Author(s): C. Amos

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