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    P46 - Novel Therapeutics and Targeted Therapies - Case Report

    • Type: Posters
    • Track: Novel Therapeutics and Targeted Therapies
    • Presentations: 7
    • Coordinates: 9/08/2021, 00:00 - 00:00, ePoster Hall
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      P46.01 - Progression After Targeted-therapy – An EGFR Case Report

      00:00 - 00:00  |  Presenter: Francisco Neri

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      P46.02 - Impact of Real-World DNA- and RNA-Based Rebiopsy Testing in EGFR-Mutated NSCLC Progressing on Osimertinib.

      00:00 - 00:00  |  Presenter: Edyta Maria Urbanska

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      P46.03 - Targeting ROS1 Gene Rearrangement by Crizotinib as Neoadjuvant Treatment Before Definitive Radiotherapy in Locally Advanced NSCLC

      00:00 - 00:00  |  Presenter: Jens Benn Sørensen

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      P46.04 - Different Effects of Crizotinib Treatment in Three Lung Adenocarcinoma Patients With Various ROS1 Fusion Variants

      00:00 - 00:00  |  Author(s): Yoko Nakanishi

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      P46.05 - Durable Response to Double Dose Osimertinib 160mg in EGFR-Mutated Non-Small Cell Lung Cancer With Brain Metastases

      00:00 - 00:00  |  Presenter: Myungwoo Nam

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      P46.06 - Response of an Advanced Lung Cancer Mass to Targeted Therapy

      00:00 - 00:00  |  Presenter: Paulo Alfredo Casanova Schulze

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      P46.07 - Afatinib-Related Pneumonitis in Metastatic EGFR-Positive NSCLC

      00:00 - 00:00  |  Presenter: Sita Andarini

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    P47 - Novel Therapeutics and Targeted Therapies - Clinical Trial in Progress

    • Type: Posters
    • Track: Novel Therapeutics and Targeted Therapies
    • Presentations: 18
    • Coordinates: 9/08/2021, 00:00 - 00:00, ePoster Hall
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      P47.01 - SGNTUC-019: Phase 2 Study of Tucatinib and Trastuzumab in Solid Tumors: Lung Cancer Cohorts (Clinical Trial in Progress)

      00:00 - 00:00  |  Presenter: Martin Reck

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      P47.02 - EV-202: Phase 2 Study of Enfortumab Vedotin for Previously Treated Advanced Solid Tumors Including Non-Small Cell Lung Cancer

      00:00 - 00:00  |  Author(s): Kei Muro

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      P47.03 - Telisotuzumab Vedotin Monotherapy in Patients With Previously Treated c-Met+ Advanced Non-Small Cell Lung Cancer: Stage 2

      00:00 - 00:00  |  Presenter: Jonathan Goldman

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      P47.04 - TROPION-Lung02: Datopotamab Deruxtecan (Dato-DXd) Plus Pembrolizumab and Platinum-Based Chemotherapy in Advanced NSCLC

      00:00 - 00:00  |  Presenter: Benjamin Levy

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      P47.05 - A Phase 2 Study of Datopotamab Deruxtecan (Dato-DXd) in Advanced NSCLC With Actionable Genomic Alterations (TROPION-Lung05)

      00:00 - 00:00  |  Presenter: Melissa L Johnson

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      P47.06 - TROPION-Lung04: Datopotamab Deruxtecan (Dato-DXd) Plus Durvalumab and Platinum-Based Chemotherapy in Advanced NSCLC

      00:00 - 00:00  |  Presenter: Hossein Borghaei

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      P47.07 - KEAPSAKE Study of Telaglenastat vs Placebo Plus Standard-of-Care in 1L KEAP1/NRF2-Mutated Non-Squamous Metastatic NSCLC

      00:00 - 00:00  |  Presenter: David R. Spigel

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      P47.08 - A Phase II, Single-arm, Multicenter, Efficacy of 80 mg Osimertinib in Patients With Leptomeningeal Metastases Associated With EGFR Mutated NSCLC

      00:00 - 00:00  |  Presenter: Sehhoon Park

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      P47.09 - Tepotinib + Osimertinib for EGFR-Mutant NSCLC with Resistance to First-Line Osimertinib Due to MET amplification: INSIGHT 2

      00:00 - 00:00  |  Presenter: Christophe Dooms

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      P47.10 - Neoadjuvant Osimertinib in EGFR-Mutant Stage IIIA/B NSCLC - A Phase 2 Open-Label Pilot Study

      00:00 - 00:00  |  Presenter: Waleed Kian

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      P47.11 - COMPEL: Chemotherapy With/Without Osimertinib in Patients With EGFRm Advanced NSCLC and Progression on First-Line Osimertinib

      00:00 - 00:00  |  Presenter: Lecia V. Sequist

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      P47.12 - ALKternate: A Proof of Concept Study in ALK-Rearranged NSCLC Alternating Lorlatinib With Crizotinib After Disease Progression

      00:00 - 00:00  |  Presenter: Malinda Itchins

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      P47.13 - First-in-Human, Dose Escalation and Expansion Study of MT-6402 in Patients With PD-L1 Expressing Advanced Solid Tumors

      00:00 - 00:00  |  Presenter: David R. Spigel

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      P47.14 - Study Design of SCORPION: Multi-Center, Phase II Study Following Platinum-Based Chemotherapy Plus ICIs in Patients with NSCLC

      00:00 - 00:00  |  Presenter: Reiko Matsuzawa

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      P47.15 - A Phase IA Study of Ceritinib + Trametinib in Patients With Advanced ALK- or ROS1- Rearranged NSCLC: Preliminary Results

      00:00 - 00:00  |  Presenter: Matthew Lara

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      P47.16 - Preliminary Efficacy and Safety Results About a Phase II Trial of Afatinib and Bevacizumab in Untreated NSCLC Harboring EGFR Sensitive Mutations

      00:00 - 00:00  |  Presenter: Yu Feng

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      P47.17 - Capmatinib vs Docetaxel in Pretreated Patients With MET Exon 14 Skipping–mutated Stage IIIB/IIIC or IV NSCLC (GeoMETry-III)

      00:00 - 00:00  |  Presenter: Pierre-Jean Souquet

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      P47.18 - Almonertinib With Radiotherapy vs Concurrent Chemoradiotherapy in Unresectable Stage III EGFR-mutant NSCLC (ADVANCE Trial)

      00:00 - 00:00  |  Presenter: Nan Bi

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    P48 - Novel Therapeutics and Targeted Therapies - EGFR

    • Type: Posters
    • Track: Novel Therapeutics and Targeted Therapies
    • Presentations: 17
    • Coordinates: 9/08/2021, 00:00 - 00:00, ePoster Hall
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      P48.01 - Anlotinib Plus Docetaxel vs Docetaxel for 2nd-Line Treatment of EGFR negative NSCLC (ALTER-L018): A Randomized Phase II Trial

      00:00 - 00:00  |  Presenter: Lin Wu

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      P48.02 - Real-World Data of Dacomitinib in EGFR TKI-Naïve Patients With Advanced Epidermal Growth Factor Receptor-positive Non-small Cell Lung Cancer

      00:00 - 00:00  |  Presenter: Jinyao Zhang

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      P48.03 - Spectrum of Resistance Mechanisms to First, Second and Third Generation Tyrosine Kinase Inhibitors in EGFR Mutant NSCLC Patients

      00:00 - 00:00  |  Presenter: Moushumi Suryavanshi

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      P48.04 - EGFR Germline Mutations in Chinese Lung Cancer Patients: A Single Institutional, Retrospective Study

      00:00 - 00:00  |  Presenter: Chengzhi Zhou

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      P48.05 - Is Relapse-Free Survival at 2-Years an Appropriate Surrogate for Overall Survival at 5-Years in EGFR-mutated Resected NSCLC?

      00:00 - 00:00  |  Presenter: Miguel Garcia

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      P48.06 - A Network Meta-Analysis (MA) of First-Line Lung Cancer Treatment With Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors (TKIs)

      00:00 - 00:00  |  Presenter: Yvonne Ang

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      P48.07 - Real-World Impact of Upfront Osimertinib in Reducing Health Resource Utilization by Preventing Brain Metastases

      00:00 - 00:00  |  Presenter: Francesca Simionato

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      P48.08 - The Efficacy and Clinical Survival Outcome of Different First-Line Treatments in EGFR Mutant Non-Small Cell Lung Cancer With Brain Metastases

      00:00 - 00:00  |  Presenter: Huijuan wang

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      P48.09 - Body Mass Index Predicts Benefit From Adding Metformin to EGFR-TKIs in Patients With Lung Adenocarcinoma: Subanalysis From an RCT

      00:00 - 00:00  |  Presenter: Oscar Arrieta

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      P48.10 - Efficacy of EGFR-TKIs vs TKIs Plus Chemotherapy as First-Line Treatment in EGFR-Mutation Lung Adenocarcinoma With Liver Metastases

      00:00 - 00:00  |  Presenter: Huijuan wang

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      P48.11 - ctDNA Dynamic Detection Reveals the Advantages of EGFR Tyrosine Kinase Inhibitors Combined With Chemotherapy in NSCLC Patients

      00:00 - 00:00  |  Presenter: Weineng Feng

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      P48.12 - Concurrent Chemotherapy and First-Generation EGFR-TKI as First-Line Treatment in Advanced Lung Adenocarcinoma Harboring EGFR Mutation

      00:00 - 00:00  |  Presenter: Ziyi Xu

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      P48.13 - Clinical Factors Associated With Treatment Outcomes in EGFR Mutant Non-Small Cell Lung Cancer Patients. Real Life Experience in Argentina

      00:00 - 00:00  |  Presenter: luis Roberto basbus

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      P48.14 - Metastatic NSCLC -Re-Challenging With Fist Generation TKI After a Drug Free Holiday After Resistance to 3rd Generation TKI

      00:00 - 00:00  |  Presenter: Suryakanta Acharya

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      P48.15 - EGFR Mutated Non-Small Cell Lung Cancer Treatment Pathway – What Is the Best Way?

      00:00 - 00:00  |  Presenter: Marta Soares

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      P48.16 - The Effect and Safety of Anlotinib as a Third Line or Further Therapy in Non-Small Cell Lung Cancer Patients With Liver Metastasis

      00:00 - 00:00  |  Presenter: Yinchen Shen

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      P48.17 - Real-World Study of Patients With EGFR Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer Treated With First-Line Osimertinib

      00:00 - 00:00  |  Presenter: Jorge Nieva

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    P49 - Novel Therapeutics and Targeted Therapies - EGFR Major

    • Type: Posters
    • Track: Novel Therapeutics and Targeted Therapies
    • Presentations: 1
    • Coordinates: 9/08/2021, 00:00 - 00:00, ePoster Hall
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      P49.01 - Drug Holiday Based on Minimal Residual Disease Status After Local Therapy Following EGFR-TKI Treatment for Patients With Advanced NSCLC

      00:00 - 00:00  |  Presenter: Song Dong

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    P50 - Novel Therapeutics and Targeted Therapies - EGFR Minor

    • Type: Posters
    • Track: Novel Therapeutics and Targeted Therapies
    • Presentations: 8
    • Coordinates: 9/08/2021, 00:00 - 00:00, ePoster Hall
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      P50.01 - RELAY, Erlotinib Plus Ramucirumab in Untreated, EGFR-Mutated, Metastatic NSCLC: Outcomes by EGFR Exon 19-del Variants

      00:00 - 00:00  |  Presenter: Kazumi Nishino

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      P50.03 - A Real-World Cohort Study of EGFR TKIs in Patients with NSCLC with Uncommon EGFR mutations (UpSwinG)

      00:00 - 00:00  |  Presenter: Satoru Miura

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      P50.04 - Amivantamab in Combination With Chemotherapy in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)

      00:00 - 00:00  |  Presenter: Misako Nagasaka

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      P50.05 - Natural History and Real-World Treatment Outcomes for NSCLC Patients with EGFR Exon 20 Insertion Mutation: An IASLC- ASCO CancerLinQ Study

      00:00 - 00:00  |  Presenter: Madhusmita Behera

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      P50.06 - First-Line Therapy in NSCLC harbouring EGFR or HER2 Exon 20 Insertion Mutation. Hunting for the Best Candidate

      00:00 - 00:00  |  Author(s): Arsela Prelaj

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      P50.07 - Afatinib Treatment Response in Advanced Lung Adenocarcinomas Harboring Uncommon Mutations in Chinese Population

      00:00 - 00:00  |  Presenter: Teng Li

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      P50.08 - Targeting HER2 or EGFR Exon 20 Insertion Mutation in Lung Cancer - A Case Series from India  

      00:00 - 00:00  |  Presenter: Vivek Joseph Varughese

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      P50.09 - Characteristics and Clinical Outcomes of HER2 Mutated Non-small Cell Lung Cancer Patients Detected by NGS in Routine Clinical Practice

      00:00 - 00:00  |  Presenter: Yejeong Han

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    P51 - Novel Therapeutics and Targeted Therapies - EGFR Resistance

    • Type: Posters
    • Track: Novel Therapeutics and Targeted Therapies
    • Presentations: 7
    • Coordinates: 9/08/2021, 00:00 - 00:00, ePoster Hall
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      P51.01 - Tepotinib Plus an EGFR TKI in Patients with EGFR-mutant NSCLC and Resistance to EGFR TKIs Due to MET Amplification (METamp)

      00:00 - 00:00  |  Presenter: Chong Kin Liam

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      P51.02 - Stacking on the Targets: Secondary Resistant, Potential Targetable Genetic Alterations in Patients With Epidermal Growth Factor Receptor NSCLC

      00:00 - 00:00  |  Presenter: Nagashree Seetharamu

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      P51.03 - Oritinib (SH-1028), a Third-generation EGFR-TKI in Advanced NSCLC Patients with Positive EGFR T790M: Results of a Single-arm Phase Ib Trial

      00:00 - 00:00  |  Presenter: Caicun Zhou

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      P51.04 - Pattern of Disease Progression on Osimertinib and Subsequent Treatment in Patients with EGFR- Mutated Non-Small Cell Lung Cancer

      00:00 - 00:00  |  Presenter: Hyesook Kim

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      P51.05 - Sequential Afatinib and Osimertinib in Patients With Advanced EGFRm+ NSCLC and Acquired T790M: The Real-World UpSwinG study

      00:00 - 00:00  |  Presenter: Sanjay Popat

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      P51.06 - Outcomes of First-Line TKI Treated Advanced NSCLC with Distinct Types of EGFR Mutations: Brain Metastasis and de Novo T790M

      00:00 - 00:00  |  Presenter: Ya Zeng

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      P51.07 - Small Cell Transformation of Non Small Cell Lung Carcinoma: Tissue Biopsy Is Here to Stay!

      00:00 - 00:00  |  Presenter: Mansi Sharma

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    P52 - Novel Therapeutics and Targeted Therapies - KRAS

    • Type: Posters
    • Track: Novel Therapeutics and Targeted Therapies
    • Presentations: 5
    • Coordinates: 9/08/2021, 00:00 - 00:00, ePoster Hall
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      P52.01 - Understanding Treatment Preferences of Patients With KRAS p.G12C[LC1] [MK2] – Mutated Advanced Non-Small Cell Lung Cancer

      00:00 - 00:00  |  Presenter: Kelley Myers

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      P52.02 - High SHP2 Expression Determines the Efficacy of PD-1/PD-L1 Inhibitors in Advanced KRAS Mutant Non-Small Cell Lung Cancer

      00:00 - 00:00  |  Presenter: Hui-Bo Feng

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      P52.03 - Efficacy of Sotorasib in KRAS p.G12C-Mutated NSCLC with Stable Brain Metastases: A Post-Hoc Analysis of CodeBreaK 100

      00:00 - 00:00  |  Presenter: Suresh Ramalingam

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      P52.04 - Histone Deacetylase 6 Inhibition Reveals Metabolic Vulnerabilities in KRAS Non-Small Cell Lung Cancer

      00:00 - 00:00  |  Presenter: Catriona M Dowling

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      P52.05 - Dual RAF/MEK Inhibitor VS-6766 for Treatment of KRAS Mutant NSCLC: Novel Combinations Targeting G12C or G12V Variants

      00:00 - 00:00  |  Author(s): Silvia Coma

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    P53 - Novel Therapeutics and Targeted Therapies - Others

    • Type: Posters
    • Track: Novel Therapeutics and Targeted Therapies
    • Presentations: 8
    • Coordinates: 9/08/2021, 00:00 - 00:00, ePoster Hall
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      P53.01 - Clinical Application of NGS Technology. Therapeutic Possibilities and Future Perspectives

      00:00 - 00:00  |  Presenter: Silvia Sequero-Lopez

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      P53.02 - Efficacy and Safety of Larotrectinib in Patients With Tropomyosin Receptor Kinase (TRK) Fusion-Positive Lung Cancer

      00:00 - 00:00  |  Presenter: Alexander Drilon

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      P53.03 - The Characteristics of FGFR Genetic Aberrations in Chinese Lung Cancer Patients

      00:00 - 00:00  |  Presenter: Xiuqin Zhang

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      P53.04 - Local Therapies vs. Specific TKIs as the Initial Treatment for Oligo-Recurrent Lung Adenocarcinoma With Driver Mutations

      00:00 - 00:00  |  Presenter: Yosuke Matsuura

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      P53.05 - Inhibition of Tumor Cell Intrinsic Complement Regulatory Proteins Leads to Decreased Tumor Growth in a Mouse Model of NSCLC

      00:00 - 00:00  |  Presenter: Emily K Kleczko

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      P53.06 - A Multi-Phase Quality Initiative to Improve Processes of Care for Non-small Cell Lung Cancer (NSCLC) in US Community Cancer Centers

      00:00 - 00:00  |  Presenter: Matthew Smeltzer

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      P53.07 - Clinical and Genomic Insights Into of Chinese Lung Cancer Patients with HER2 Amplification

      00:00 - 00:00  |  Presenter: Chengzhi Zhou

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      P53.08 - Concomitant Fibrates and Immunotherapy in Non-Small Cell Lung Cancer Patients in the Veterans Health Administration

      00:00 - 00:00  |  Presenter: William A Stokes

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    P54 - Palliative and Supportive Care

    • Type: Posters
    • Track: Palliative and Supportive Care
    • Presentations: 6
    • Coordinates: 9/08/2021, 00:00 - 00:00, ePoster Hall
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      P54.01 - Analysis of the Support Needs of Lung Cancer Patients

      00:00 - 00:00  |  Author(s): Paris Kosmidis

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      P54.02 - Palliative Treatment of Tumor Stenoses of the Trachea and Bronchi

      00:00 - 00:00  |  Presenter: Vladyslav Severgin

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      P54.03 - Bilateral Indwelling Pleural Catheters

      00:00 - 00:00  |  Presenter: Avinash Aujayeb

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      P54.04 - Detecting Elevated Risk of Diminished Quality of Life Among Lung Cancer Patients by Using Wearable Devices

      00:00 - 00:00  |  Presenter: Maria Torrente

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      P54.05 - Stereotactic Radiotherapy for Brain Metastases in Patients With Lung Cancer: Cyberknife Experience

      00:00 - 00:00  |  Presenter: Süreyya Sarıhan

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      P54.06 - The FITNESS Study: Geriatric Assessment, Treatment Toxicity, and Biospecimen Collection Among Older Adults With Lung Cancer

      00:00 - 00:00  |  Presenter: Madison Grogan

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    P55 - Patient Advocacy

    • Type: Posters
    • Track: Patient Advocacy
    • Presentations: 3
    • Coordinates: 9/08/2021, 00:00 - 00:00, ePoster Hall
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      P55.01 - Standard of Care Disparity in a Global Cancer Support Group: Examining an Advocate Survey to Inspire Change.

      00:00 - 00:00  |  Presenter: Jamie Gibbard

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      P55.02 - Robotic Surgery in Canada: Are Patients Willing to Pay Out-of-Pocket?

      00:00 - 00:00  |  Presenter: Yogita S. Patel

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      P55.03 - Results of The First Survey Using EORTC QLQ INFO25 on Information Acquisition and Satisfaction of Lung Cancer Patients in Japan

      00:00 - 00:00  |  Presenter: Takayuki Takahama

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