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yuanqiang Zhang
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P32 - Palliative and Supportive Care - Misc. Topics (ID 220)
- Event: WCLC 2020
- Type: Posters
- Track: Palliative and Supportive Care
- Presentations: 1
- Moderators:
- Coordinates: 1/28/2021, 00:00 - 00:00, ePoster Hall
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P32.06 - Investigation of the Current Use of Opioid Analgesics After Lung Resection and the Analysis of Its Influencing Factors (ID 3359)
00:00 - 00:00 | Presenting Author(s): yuanqiang Zhang
- Abstract
Introduction
The use of opioid analgesics after lung resection is unclear in China. This study aimed to investigate the current use of opioid analgesics after lung resection and analyseits influencing factors.Table 2.Analgesic information
Name of analgesics
Number
Percentage
Opioids
448
99.6%
Weak opioids
38
8.4%
Codeine tablets
3
0.7%
Codeine oral liquid
37
8.2%
Strong opioids
437
97.1%
Morphine hydrochloride tablet
0
0%
Fentanyl transdermal patch
0
0%
Oxycodone hydrochloride sustained release tablets
2
0.4%
Morphine Sulfate Sustained-release Tablets
5
1.1%
fentanyl
0
0%
Sufentanil
323
71.8%
Remifentanil
70
15.6%
morphine
74
16.4%
Oxycodone
0
0.0%
Butorphanol
311
69.1%
Dezocine
206
45.8%
Bucinazine
29
6.4%
Pethidine
0
0%
Compound
369
82.0%
Lofenadine sustained release tablets
369
82.0%
Methods
The clinical data of 450 patients undergoing lung resection at Sichuan Cancer Hospital from November 2017 to November 2019 were analysed retrospectively. Various opioid analgesics were converted into oral morphine milligram equivalents. Multiple linear regression was performed to determine its influencing factors.
Results
Of the 450 patients, 448 (99.56%) used opioid analgesics; 8.4% used weak opioids, 97.1% used strong opioids and 82% used compoundanalgesics.The mean daily morphine equivalent dose during hospitalization was 48.9 mg. There were significant differences in postoperative morphine equivalent dose across patients with different sex, age,operative time,length of hospital stay, educational level, comorbidity score, surgical approach, surgical extentand postoperative complication grade (P< 0.05). Multivariate analysis showed that sex, length of hospital stay and surgical approach were independent influencing factors for postoperative morphine use.
Conclusion
This study provided a baseline reference for the use of opioid analgesics after lung resection in China. In clinical practice, attention should be paid to postoperative analgesia for male patients, to promote the application of minimally invasive surgical approach, and tominimize the length of hospital stay, in order to ultimately reduce the use of opioids.
