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Lawrence Cyril Gaudiel Vitug
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P30 - Palliative and Supportive Care (ID 163)
- Event: WCLC 2020
- Type: Posters
- Track: Palliative and Supportive Care
- Presentations: 1
- Moderators:
- Coordinates: 1/28/2021, 00:00 - 00:00, ePoster Hall
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P30.10 - Local Pulmonary Administration of Tranexamic Acid as Inhalational or Nebulized for the Control of Hemoptysis: A Systematic Review of Case Reports, Case Series, and an RCT (ID 2871)
00:00 - 00:00 | Presenting Author(s): Lawrence Cyril Gaudiel Vitug
- Abstract
Introduction
Hemoptysis is defined as the expectoration of blood from the respiratory tract. It has various and broad etiologies. Current definitive management of pulmonary hemorrhage, such as bronchoscopic and surgical interventions, are not readily available in rural settings and not all referral centers are capable of doing such interventions.
Methods
The authors specifically reviewed all case reports, case series of patients and 1 available Randomized Controlled Trial whom Tranexamic Acid was used as inhalational or nebulized and was used as treatment for hemoptysis.
Results
There is limited and paucity of data describing its use, wherein only limited case report, case series and one Randomized Controlled Trial were available. The review suggests that local administration of Tranexamic Acid, either through inhalational or nebulization, is an effective, safe, and easy-to-formulate mode of administration to control the hemoptysis of various etiologies.
Conclusion
The nebulized Tranexamic Acid is a viable option for the control of hemoptysis in emergency rooms and hospitals. It is a potential bridging agent in the control hemoptysis in low resource setting. However due to limited and paucity of data, it recommended that more studies be conducted in the potential use of nebulized Tranexamic Acid.
It is a viable and potential option for the control of hemoptysis in emergency rooms, hospitals. It is a potential bridging agent in the control hemoptysis in low resource setting.
However due to limited and paucity of data, no cause-and-effect relationship can be concluded. It is recommended that more studies be conducted in the potential use of nebulized Tranexamic Acid.