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Frank Detterbeck



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    MS03 - Workup and Management of Small Anterior Mediastinal Masses/Lesions (ID 66)

    • Event: WCLC 2019
    • Type: Mini Symposium
    • Track: Thymoma/Other Thoracic Malignancies
    • Presentations: 1
    • Now Available
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      MS03.02 - Resection, Biopsy or Observation of Small Anterior Mediastinal Lesions (Now Available) (ID 3450)

      13:30 - 15:00  |  Presenting Author(s): Frank Detterbeck

      • Abstract
      • Presentation
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      Abstract

      With greater prevalence of CT scanning for many reasons, the incidental detection of a prevascular lesions has increased markedly. 3 sources of data show the incidence to be around 0.5-1% in asymptomatic adults. There is no accepted standard for how to manage these patients, and until recently there was little data to base an approach on. Recently, examination of scans done for lung cancer screening provide some answers. The majority of these lesions have CT characteristics that are consistent with a thymic epithelial tumor (TET). However, the vast majority are stable over a median follow-up of approximately 5 years. While a minority exhibit growth, on further observation most of these do not continue to grow or decrease in size. It is well documented that thymic cysts and other benign lesions sometimes grow slightly. The overall incidence of a malignancy is around 2%. Even after a prolonged period of observation, when resection is undertaken for a TET, the vast majority are stage I (8th edition of TNM) and there have been no recurrences over a median follow up of approximately 5 years. This has been the case even with thymic carcinoma. In summary, simple observation of incidentally discovered prevascular lesions appears to be safe, without losing a window for intervention in the small percentage of patients that need this.

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