Author of

• 28123

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  Best abstracts selected from submissions 3 (ID 3)

  • Event: ACLC 2018
  • Type: Oral Session
  • Track:
  • Presentations: 1
  • Moderators:
  • Coordinates: 11/08/2018, 16:20 - 17:00, Crystal Ballroom 1

  • 28224

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    OA05 - Tumor Mutational Burden Standardization Initiative: Establish a Consistent Methodology for TMB Measurement in Clinical Samples (ID 217)

    16:20 - 17:00  |  Author(s): F Yan
    • Abstract

    Background:
    Clinical studies have established Tumor Mutational Burden (TMB), a measurement of mutations in the tumor genome, as a predictive biomarker for clinical efficacy of immune checkpoint inhibitors (ICIs). There is a lack of standardization for TMB estimation and reporting, which is critical for ensuring consistency for clinical implementation. An international collaboration organized by Friends of Cancer Research (Friends) and Qualit