Author of

• 13580

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  P1.04 - Poster Session/ Biology, Pathology, and Molecular Testing (ID 233)

  • Event: WCLC 2015
  • Type: Poster
  • Track: Biology, Pathology, and Molecular Testing
  • Presentations: 1
  • Moderators:
  • Coordinates: 9/07/2015, 09:30 - 17:00, Exhibit Hall (Hall B+C)

  • 13623

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    P1.04-043 - Pulmonary Lepidic Adenocarcinoma in a Patient with Prior Diagnosis of Breast Cancer: Case Report (ID 1289)

    09:30 - 17:00  |  Author(s): M. Velasquez
    • Abstract
    • Slides

    Background:
    The combined effect of improved cancer diagnosis and management has led to a marked increase in cancer survivors. Consequently, an appreciable proportion of cancer diagnoses are registered among patients who had already received a cancer diagnosis in the past, and more accurate diagnostic procedures lead to the identification of more than one cancer in a subset of patients. We present the case of a patient with breast cancer in whom a lepidic primary lung adenocarcinoma was discovered during a follow-up.
    
    Methods:
    Medical History Revission
    
    Results:
    A 68-years-old female with breast cancer EC EIII diagnosed in March / 2010, handled with lumpectomy and lymph node removal, solid mucinous ductal carcinoma Ki67 expression: 35% RH: E (+) 100%, P (-), HER 2 NEU negative, negative margins with angiolymphatic invasion 3/15. She received radiotherapy, tamoxifen and later anastrozole. In Dec / 2010 she presents tumor recurrence managed with radical mastectomy, received chemotherapy with Adriamycin and Cyclophosphamide. In April / 2013 she consults with two months of dry cough and dyspnea, normal physical examination, an unremarkable mammography, chest CT-scan with irregular right basal nodular lesion and mediastinal nodes. The patient underwent resection through thoracoscopy, pathology shows lepidic adenocarcinoma pattern with mutated EGFR exon 19 and exon 21 negative, with metastatic nodal involvement by the primary lung tumor and previous breast carcinoma.
    
    Conclusion:
    Patients that have been diagnosed with a cancer, have an increased lifetime risk for developing another de novo malignancy depending on various inherited, environmental and iatrogenic risk factors. Cancer patients could survive longer due to settling treatment modalities, and then would likely develop a new malignancy. The monitoring and evaluation procedures are especially useful for early detection of tumors associated when there’s a known tumor lesion. Figure 1Figure 2
    
    
    
    
    
    

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