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N.S. Lam



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    P1.04 - Poster Session/ Biology, Pathology, and Molecular Testing (ID 233)

    • Event: WCLC 2015
    • Type: Poster
    • Track: Biology, Pathology, and Molecular Testing
    • Presentations: 1
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      P1.04-042 - Diagnostic Role of Immunocytochemistry in Malignant Pleural Mesothelioma (ID 51)

      09:30 - 17:00  |  Author(s): N.S. Lam

      • Abstract
      • Slides

      Background:
      Malignant pleural mesothelioma is a difficult diagnosis, more severe cases may not perform by pleural biopsy. With these cases, the technique of immunocytochemistry was performed proposals.

      Methods:
      A prospective, cross-sectional descriptive statistics with clinical series cases.

      Results:
      § Implementing 58 cases of malignant pleural mesothelioma by immunocytochemistry. § Technical Cytospin method has helped for immunocytochemistry have high results. § Should be done more staining with markers for the other diagnostic diseases: lung cancer and non-lung cancers that metastatic to pleura. § The results of the data : - Sensitivity: 84.06 % - Specificity : 100 % - Positive Prognostic Value : 100 % - Negative Prognostic Value : 92.25 % - Accuracy : 94.12 %

      Conclusion:
      The diagnosis of malignant pleural mesothelioma is always a difficult diagnosis. Needing the differential diagnosis with other types of diseases, such as lung cancer and non-lung cancers that to pleural pulmonary metastases. Staining with immunocytochemistry in cases of pleural effusion showed relatively high value. This suggests that the ability to diagnose initially screening properties of this technique is very good, especially valuable in the diagnosis of severe disease progression can not perform other diagnostic techniques.

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