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  P3.04 - Poster Session with Presenters Present (ID 474)

  • Event: WCLC 2016
  • Type: Poster Presenters Present
  • Track: Surgery
  • Presentations: 1
  • Moderators:
  • Coordinates: 12/07/2016, 14:30 - 15:45, Hall B (Poster Area)

  • 18716

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    P3.04-046 - Cases of Surgical Resection of Post-Operative Lymph Node Recurrences from Primary Lung Cancer (ID 5317)

    14:30 - 15:45  |  Author(s): D. Okutani
    • Abstract
    • Slides

    Background:
    The prognosis of patients with recurrent nodal metastasis after resection of primary lung cancer is poor, and surgical resection is not indicated for patients with lymph node (LN) disease beyond N3. Recently, some reports showed the efficacy of surgical resection of the small number of distant metastases (oligometastasis). In our hospital, we had 7 cases of nodal metastasis resection after primary lung cancer resection. The purpose of this study was to discuss the possibility of improving prognosis by resection of nodal recurrence.
    
    Methods:
    From 2007 to 2013, we examined 7 patients for whom lymphadenectomy was performed to treat lymph nodal recurrence following curative resection of the primary cancer at our hospital.The mean age was 58 years(45-73 years);there were 2 female and 5 male patients.At the initial operation,there was 1 case of stageⅡA,1 case of stageⅡB,4 cases of stageⅢA,1case of stageⅢB cancer.Pathologically,there ware 3 adenocarcinoma cases,3 squamous cell carcinoma cases,and 1 adenosquamous carcinoma case.All patients underwent postoperative adjuvant chemotherapy, and 4 patients underwent postoperative radiotherapy for residual or recurrent tumors.
    
    Results:
    All 7 patients underwent lymphadenectomy;3 had supraclavicular recurrent LN and 4 had mediastinal recurrent LN.In 2 of the supraclavicular cases and 1 of the mediastinal cases,the patients are alive without any recurrence.In the other four cases,the patients showed re-recurrence,received chemotherapy,and are alive.The median survival time from the day of recurrent lymphadenectomy was 32 months (27-62months) and that from the day of the initial operation was 76 months (36-101months).The median disease-free survival time from the day of recurrent lymphadenectomy was 19 months (9-62months).The 2 years disease-free survival was 42.9%. The median interval from initial operation to recurrent lymphadenectomy was 43.3 months for the 3 cases without recurrence and 19.8 months for the 4 cases with re-recurrence
    
    Conclusion:
    Complete cure or better prognosis could be expected via surgical resection for some cases with LN recurrence when the lesion is localized and has no distant metastasis.A longer interval between initial operation and the day of recurrence might indicate better prognosis. Therefore,surgical resection of LN recurrence might be indicated if other metastatic lesions do not occur after a certain period.
    
    

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