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  • TTLC 2020

    Targeted Therapies in Lung Cancer 2020

    Access to all slides from presentations that occur during the IASLC 2020 Targeted Therapies of Lung Cancer Meeting in Santa Monica, CA

    Presentation Date(s):  
    • February 19 – 22, 2020
    • Total Presentations: 230

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    S07 - Stage 3 NSCLC/Combined Modality Therapy

    • Type: General Session
    • Track:
    • Presentations: 11
    • Slides Available
    • Coordinates: 2/21/2020, 08:50 - 09:55,
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      PACIFIC Trials (Slides Available)

      08:50 - 08:55  |  Author(s): Everett Vokes

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      Chemo-RT plus Pembrolizumab (Slides Available)

      08:55 - 09:00  |  Author(s): Greg Durm

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      ECOG-ACRIN 5181 (Chemo-RT plus Durva) (Slides Available)

      09:00 - 09:05  |  Author(s): Nathan Pennell

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      RT + Atezolizumab (Slides Available)

      09:05 - 09:10  |  Author(s): Christine Bestvina

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      RT plus Durva for high PD-L1 Exp NSCLC NRG LU004 (Slides Available)

      09:10 - 09:15  |  Author(s): Steven Lin

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      Chemo RT plus PARP inhibition (Slides Available)

      09:15 - 09:20  |  Author(s): Primo Lara

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      Chemo RT + Metformin

      09:20 - 09:25  |  Author(s): Theodoros Tsakiridis

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      Chemo RT followed by Targeted Therapy: LAURA Study (Slides Available)

      09:25 - 09:30  |  Author(s): Suresh Ramalingam

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      RTOG 1308: Proton Vs. Photon (Slides Available)

      09:30 - 09:35  |  Author(s): Jeffrey Bradley

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      RT for oligometastatic NSCLC (NRG LU002) (Slides Available)

      09:35 - 09:40  |  Author(s): Kristin Higgins

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      SBRT + Immunotherapy (Slides Available)

      09:40 - 09:45  |  Author(s): Roy Decker

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    D04 - Should RT be given for a patient responding to IO for oligometastatic NSCLC?

    • Type: General Session
    • Track:
    • Presentations: 2
    • Slides Available
    • Coordinates: 2/21/2020, 10:15 - 10:35,
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      Yes (Slides Available)

      10:15 - 10:25  |  Author(s): Puneeth Iyengar

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      No

      10:25 - 10:35  |  Author(s): Walter Curran Jr.

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    S08 - Antibody Drug Conjugates

    • Type: General Session
    • Track:
    • Presentations: 11
    • Slides Available
    • Coordinates: 2/21/2020, 10:35 - 11:35,
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      Science (Slides Available)

      10:35 - 10:45  |  Author(s): Pasi Janne

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      DS-1062 (Trop-2) (Slides Available)

      10:45 - 10:50  |  Author(s): Jacob Sands

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      DS1205 (AXL) (Slides Available)

      10:50 - 10:55  |  Author(s): Helena Yu

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      IMMUNO132 (Trop-2) (Slides Available)

      10:55 - 11:00  |  Author(s): Ross Camidge

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      Enapotamab Vedotin (Slides Available)

      11:00 - 11:05  |  Author(s): Hossein Borghaei

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      ABBV399 (MET) (Slides Available)

      11:05 - 11:10  |  Author(s): Jyoti Patel

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      DS8201 (HER2) (Slides Available)

      11:10 - 11:15  |  Author(s): Jose Pacheco

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      ADCT502 (HER2) (Slides Available)

      11:15 - 11:20  |  Author(s): Grace Dy

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      BGB324 (AXL TKI) (Slides Available)

      11:20 - 11:25  |  Author(s): David Gerber

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      U3-1402 (HER3-directed ADC) (Slides Available)

      11:25 - 11:30  |  Author(s): Conor Steuer

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      XMT1536 (NaPi2b) (Slides Available)

      11:30 - 11:35  |  Author(s): Melissa Johnson

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    S09 - FGFR/PDFGR/Angiogenesis/VEGF

    • Type: General Session
    • Track:
    • Presentations: 8
    • Slides Available
    • Coordinates: 2/21/2020, 11:45 - 12:40,
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      Science (Slides Available)

      11:45 - 11:55  |  Author(s): John Heymach

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      Nivolumab + vorolanib (Slides Available)

      11:55 - 12:00  |  Author(s): Heather Wakelee

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      Nivolumab + sitravantinib (Slides Available)

      12:00 - 12:05  |  Author(s): Kai He

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      EGFR + Bevacizumab or Ramicurumab (Slides Available)

      12:05 - 12:10  |  Author(s): Balazs Halmos

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      Ramacirumab + IO (Slides Available)

      12:10 - 12:15  |  Author(s): Rathi Pillai

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      Cabozantinib (Slides Available)

      12:15 - 12:20  |  Author(s): Heather Wakelee

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      Nintedanib + IO (Slides Available)

      12:20 - 12:25  |  Author(s): Erin Schenk

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      Nintedanib for mutations and its receptors

      12:25 - 12:30  |  Author(s): Ticiana Leal

      • Abstract

      No abstract available for this presentation

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    OA - Best Abstracts - Oral Presentations

    • Type: General Session
    • Track:
    • Presentations: 5
    • Slides Available
    • Coordinates: 2/21/2020, 13:40 - 14:40,
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      Impact of DNA damage response and repair (DDR) gene mutations on efficacy of PD-(L)1 immune checkpoint inhibition in non-small cell lung cancer (Slides Available)

      13:40 - 13:48  |  Author(s): Biagio Ricciuti

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      Interferon Gamma Resistance in Setting of LKB1 Loss: Phenotypic Characterization and Investigation of Mechanism (Slides Available)

      13:48 - 13:56  |  Author(s): Jacob Kaufman

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      Detection of NRG1 gene fusions in NSCLC (Slides Available)

      13:56 - 14:04  |  Author(s): Sushma Jonna

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      Targeting inflammatory monocytes with dual CCR2/5 inhibition in combination with immune checkpoint inhibition in lung squamous carcinoma (Slides Available)

      14:04 - 14:12  |  Author(s): Yvonne Chao

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      MSK-ACCESS for non-invasive somatic mutation profiling of lung cancers utilizing circulating tumor DNA: A prospective clinical study

      14:12 - 14:20  |  Author(s): Emily Lebow

      • Abstract

      No abstract available for this presentation

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    S10 - ROS1, TRK, ALK, NRG Fusions

    • Type: General Session
    • Track:
    • Presentations: 14
    • Slides Available
    • Coordinates: 2/21/2020, 14:40 - 16:05,
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      Science

      14:40 - 14:50  |  Author(s): Alexander Drilon

      • Abstract

      No abstract available for this presentation

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      Entrectinib (Slides Available)

      14:50 - 14:55  |  Author(s): Robert Doebele

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      Repotrectinib (Slides Available)

      14:55 - 15:00  |  Author(s): Sai-Hong Ou

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    • +

      Crizotinib (Slides Available)

      15:00 - 15:05  |  Author(s): Jessica Lin

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      Lorlatinib (Slides Available)

      15:05 - 15:10  |  Author(s): Christine Lovly

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      DS6051b (Slides Available)

      15:10 - 15:15  |  Author(s): Elaine Shum

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      Ceritinib +/- Trametinib (Slides Available)

      15:15 - 15:20  |  Author(s): Caroline McCoach

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      Larotrectinib (Slides Available)

      15:20 - 15:25  |  Author(s): Anna Farago

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      Loxo 195

      15:25 - 15:30  |  Author(s): Alexander Drilon

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      No abstract available for this presentation

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      Ensartinib (Slides Available)

      15:30 - 15:35  |  Author(s): Leora Horn

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      Brigatinib (Slides Available)

      15:35 - 15:40  |  Author(s): Thomas Stinchcombe

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      Alectinib + bev or other (Slides Available)

      15:40 - 15:45  |  Author(s): Justin Gainor

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      IO post TKI (Slides Available)

      15:45 - 15:50  |  Author(s): Corey Langer

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      NRG1 fusion Inhibitors (Slides Available)

      15:50 - 15:55  |  Author(s): Stephen Liu

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    S11 - RET/MET Inhibitors

    • Type: General Session
    • Track:
    • Presentations: 14
    • Slides Available
    • Coordinates: 2/21/2020, 16:25 - 17:50,
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      Science (Slides Available)

      16:25 - 16:35  |  Author(s): Robert Doebele

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      BLU667 (RET) (Slides Available)

      16:35 - 16:40  |  Author(s): Justin Gainor

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      Loxo292 selpercatinib (RET) (Slides Available)

      16:40 - 16:45  |  Author(s): Alexander Drilon

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      TPX-0046 (RET) (Slides Available)

      16:45 - 16:50  |  Author(s): Misako Nagasaka

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      RXDX105 (Slides Available)

      16:50 - 16:55  |  Author(s): Antoinette Wozniak

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      Crizotinib (MET) (Slides Available)

      16:55 - 17:00  |  Author(s): Mark Kris

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      Savolitinib (MET) (Slides Available)

      17:00 - 17:05  |  Author(s): Mark Awad

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      Topotinib (MET) (Slides Available)

      17:05 - 17:10  |  Author(s): Xiuning Le

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      Capmatinib (MET) (Slides Available)

      17:10 - 17:15  |  Author(s): Rebecca Heist

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      TPX0022 (MET/CSFR1/SRC) (Slides Available)

      17:15 - 17:20  |  Author(s): Sandip Patel

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      APL-101 (Slides Available)

      17:20 - 17:25  |  Author(s): Aaron Mansfield

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      Merestinib (Slides Available)

      17:25 - 17:30  |  Author(s): Julia Rotow

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      REGN 5093 (Slides Available)

      17:30 - 17:35  |  Author(s): Thomas Marron

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      Sym015 (MET) (Slides Available)

      17:35 - 17:40  |  Author(s): Ross Camidge

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    S12 - Mesothelioma

    • Type: General Session
    • Track:
    • Presentations: 6
    • Slides Available
    • Coordinates: 2/21/2020, 16:25 - 17:50,
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      Science (Slides Available)

      17:50 - 18:00  |  Author(s): Harvey Pass

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      Brentuximab (Slides Available)

      18:00 - 18:05  |  Author(s): Anne Tsao

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      Anetumab Ravtansine + Pembrolizumab (Slides Available)

      18:05 - 18:10  |  Author(s): Kaushal Parikh

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      WT1 Peptide Vaccine and CAR (Slides Available)

      18:10 - 18:15  |  Author(s): Matthew Gubens

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      Chemo + IO (Slides Available)

      18:15 - 18:20  |  Author(s): Patrick Forde

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      Neoadjuvant chemo-IO (Slides Available)

      18:20 - 18:25  |  Author(s): Anne Tsao

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    S13 - Immunotherapy Combinations

    • Type: General Session
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    • Presentations: 24
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    • Coordinates: 2/22/2020, 07:00 - 09:15,
    • +

      Science (Slides Available)

      07:00 - 07:10  |  Author(s): Edward Garon

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      CTLA4 combinations (Slides Available)

      07:10 - 07:15  |  Author(s): Jarushka Naidoo

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      PD1 and ICOS (Slides Available)

      07:15 - 07:20  |  Author(s): Charu Aggarwal

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      IO + LAG3 (Slides Available)

      07:20 - 07:25  |  Author(s): Ashwin Somasundaram

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      IO + CD137 (Slides Available)

      07:25 - 07:30  |  Author(s): Adrian Sacher

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      IO + CDX1140 (anti-CD40) (Slides Available)

      07:30 - 07:35  |  Author(s): Rachel Sanborn

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      IO + OX40 (Slides Available)

      07:35 - 07:40  |  Author(s): Narjust Duma

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      LYC44716 (Slides Available)

      07:40 - 07:45  |  Author(s): Scott Gettinger

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      Pembrolizumab + vorinostat (Slides Available)

      07:45 - 07:50  |  Author(s): Ben Creelan

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      IO+ Epacadostat (Slides Available)

      07:50 - 07:55  |  Author(s): Liza Villaruz

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      Pembrolizumab and itacitinib (JAK1) (Slides Available)

      07:55 - 08:00  |  Author(s): Joshua Bauml

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      Atezolizumab + Cobimetinib (Slides Available)

      08:00 - 08:05  |  Author(s): Ryan Gentzler

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      MGA271 (Slides Available)

      08:05 - 08:10  |  Author(s): Konstantinos Leventakos

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      Phase I Study of TJ004309 (anti-CD73) in combination with atezolizumab in advanced cancers (Slides Available)

      08:10 - 08:15  |  Author(s): Francisco Robert

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      TRQ15-01 (Slides Available)

      08:15 - 08:20  |  Author(s): Melissa Johnson

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      IO + CCR2/5 Inhibitors (Slides Available)

      08:20 - 08:25  |  Author(s): Chad Pecot

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      Siglec 15 (Slides Available)

      08:25 - 08:30  |  Author(s): Roy Herbst

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    • +

      CB 839

      08:30 - 08:35  |  Author(s): Aaron Lisberg

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    • +

      Pinabulin (Slides Available)

      08:35 - 08:40  |  Author(s): Lyudmila Bazhenova

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      Monalizumab (Slides Available)

      08:40 - 08:45  |  Author(s): Joshua Reuss

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      Comparing effect of IO combinations (Slides Available)

      08:45 - 08:50  |  Author(s): Jack Lee

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      Afatinib + Pembro (Slides Available)

      08:50 - 08:55  |  Author(s): Benjamin Levy

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      IO + GSK3377794 (Slides Available)

      08:55 - 09:00  |  Author(s): Ronan Kelly

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    • +

      PY314 – anti-TREM2 antibody

      09:00 - 09:05  |  Author(s): Erin Schenk

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  • +

    S14 - mTOR/PI3K/CDK/DNA repair/CHK1/Wee1/PARP inhibition

    • Type: General Session
    • Track:
    • Presentations: 21
    • Slides Available
    • Coordinates: 2/22/2020, 09:30 - 11:25,
    • +

      Rucaparib (Slides Available)

      09:30 - 09:35  |  Author(s): Shirish Gadgeel

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      Prexasertib (Slides Available)

      09:35 - 09:40  |  Author(s): Stephen Liu

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    • +

      TAK228 (Sapanisertib) (Slides Available)

      09:40 - 09:45  |  Author(s): Jonathan Riess

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      Taselisib (Slides Available)

      09:45 - 09:50  |  Author(s): Corey Langer

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      Gedatolisib (Slides Available)

      09:50 - 09:55  |  Author(s): Zofia Piotrowska

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      ABTL 0812 (Slides Available)

      09:55 - 10:00  |  Author(s): George Blumenschein

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    • +

      mTOR inhibition +PD-1 inhibition (Slides Available)

      10:00 - 10:05  |  Author(s): Fadlo Khuri

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      PI3K inhibition + PD-1 inhibition (Slides Available)

      10:05 - 10:10  |  Author(s): Jennifer Carlisle

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    • +

      Sapanisertib + CB-839 (Slides Available)

      10:10 - 10:15  |  Author(s): Jonathan Riess

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    • +

      Sirolimus + Auranofin (Slides Available)

      10:15 - 10:20  |  Author(s): Helen Ross

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      Trilaciclib (Slides Available)

      10:20 - 10:25  |  Author(s): Jeffrey Crawford

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    • +

      MK 8628 & GSK 525762 (Slides Available)

      10:25 - 10:30  |  Author(s): Taofeek Owonikoko

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    • +

      Olaparib (Slides Available)

      10:30 - 10:35  |  Author(s): Ben Creelan

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    • +

      Talazoparib (Slides Available)

      10:35 - 10:40  |  Author(s): Taofeek Owonikoko

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    • +

      Niraparib (Slides Available)

      10:40 - 10:45  |  Author(s): Zofia Piotrowska

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    • +

      VX-970 (Slides Available)

      10:45 - 10:50  |  Author(s): Deborah Doroshow

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      AZD 6738 (Slides Available)

      10:50 - 10:55  |  Author(s): Daniel Morgensztern

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      BAY 1895344 (Slides Available)

      10:55 - 11:00  |  Author(s): Timothy Yap

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      Adavosertib (AZD1775) (Slides Available)

      11:00 - 11:05  |  Author(s): Dwight Owen

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      AZD 0156 (Slides Available)

      11:05 - 11:10  |  Author(s): Patricia LoRusso

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      DNA PK inhibition (Slides Available)

      11:10 - 11:15  |  Author(s): George Simon

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