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  • WCLC 2015

    16th World Conference on Lung Cancer

    Access to all presentations that occur during the 16th World Conference on Lung Cancer in Denver, Colorado

    Presentation Date(s):  
    • September 6 - 9, 2015
    • Total Presentations: 2499

    To review abstracts of the presentations below, narrow down your search by using the Filter options below, and then select the session listing of your choice. Click the "+" for a presentation to expand & view the corresponding Abstract details.

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    MINI 02 - Immunotherapy

    • Type: Mini Oral
    • Track: Biology, Pathology, and Molecular Testing
    • Presentations: 14
    • Moderators:P. Forde
    • Coordinates: 9/07/2015, 10:45 - 12:15, Four Seasons Ballroom F3+F4
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      MINI02.01 - Pulmonary Large Cell Carcinoma and Solid Adenocarcinoma Are Highly Mutated with Frequent Expression of PDL1

      10:45 - 10:50  |  Author(s): D.H. Hwang

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      MINI02.02 - Programmed Cell Death Ligand (PD-L1) Expression in Stage II and III Lung Adenocarcinomas and Nodal Metastases

      10:50 - 10:55  |  Author(s): H. Uruga

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      MINI02.03 - Overexpression of CD47, Decrease of Apoptosis and Phagocytosis of Neutrophils in Advanced Non-Small Cell Lung Cancer Patients

      10:55 - 11:00  |  Author(s): L. Barrera

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      MINI02.04 - Sequential Assessment of DNA Damage Response and PD-L1 Expression in Circulating Tumor Cells of Lung Cancer Patients during Radiotherapy

      11:00 - 11:05  |  Author(s): S.H. Lin

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      MINI02.05 - Discussant for MINI02.01, MINI02.02, MINI02.03, MINI02.04

      11:05 - 11:15  |  Author(s): D.P. Carbone

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      MINI02.06 - Humanized Immuno-Mouse for Study of Anti-PD-1 Therapy in KRAS-Mutated Lung Cancer Patient Derived Xenotransplant (PDX)

      11:15 - 11:20  |  Author(s): M. Wang

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      MINI02.07 - Preclinical Rationale for a Phase I/II Study of Pembrolizumab (P) and Vorinostat (V) in Immune Therapy Naïve and Pretreated Stage IV NSCLC

      11:20 - 11:25  |  Author(s): N. Tchekmedyian

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      MINI02.08 - Bidirectional Cross-Talk between CD14+ Monocytes and Human Lung Cancer Cell Lines Results in Different Phenotypic and Functional Outcomes

      11:25 - 11:30  |  Author(s): E. Schenk

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      MINI02.09 - ERK Activation Mediates Increased PD-L1 Expression in KRAS Mutated Premalignant Human Bronchial Epithelial Cells

      11:30 - 11:35  |  Author(s): M. Lee

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      MINI02.10 - Discussant for MINI02.06, MINI02.07, MINI02.08, MINI02.09

      11:35 - 11:45  |  Author(s): I.I. Wistuba

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      MINI02.11 - Immunological Markers Predict the Prognosis of Patients with Squamous Non-Small Cell Lung Cancer

      11:45 - 11:50  |  Author(s): L. Jiang

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      MINI02.12 - Distribution of Immune Markers and Their Association with Overall Survival and Time to Progression in Non-Small-Cell Lung Cancer (NSCLC)

      11:50 - 11:55  |  Author(s): A.T. Kuykendall

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      MINI02.13 - Immune Related Gene Signature Reveal Potential Role for Leukocyte-Associated Immunoglobin-Like Receptor 2 (LAIR2) in Lung Cancer Regulation

      11:55 - 12:00  |  Author(s): D. Ly

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      MINI02.14 - Discussant for MINI02.11, MINI02.12, MINI02.13

      12:00 - 12:10  |  Author(s): V. Papadimitrakopoulou

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    ORAL 01 - Chemotherapy Developments for Lung Cancer

    • Type: Oral Session
    • Track: Treatment of Advanced Diseases - NSCLC
    • Presentations: 7
    • Moderators:G. Blumenschein
    • Coordinates: 9/07/2015, 10:45 - 12:15, 401-404
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      ORAL01.01 - Randomized Phase III Study of Nedaplatin plus Docetaxel versus Cisplatin plus Docetaxel for Advanced Squamous Cell Lung Cancer (WJOG5208L)

      10:45 - 10:56  |  Author(s): T. Seto

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      ORAL01.02 - Therapy of Advanced Metastatic Lung Cancers with an Anti-Trop-2-SN-38 Antibody-Drug Conjugate, IMMU-132: Interim Phase II Clinical Results

      10:56 - 11:07  |  Author(s): R. Camidge

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      ORAL01.03 - A Randomized Phase 2 Trial of Vintafolide and Docetaxel in Folate-Receptor Positive (FR+) Advanced NSCLC Patients: Final Efficacy Results

      11:07 - 11:18  |  Author(s): N. Hanna

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      ORAL01.04 - Discussant for ORAL01.01, ORAL01.02, ORAL01.03

      11:18 - 11:28  |  Author(s): M. Boyer

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      ORAL01.05 - Phase I/II Dose Escalation Study of Immunoconjugate L-DOS47 as a Monotherapy in Non-Squamous Non-Small Cell Lung Cancer Patients

      11:28 - 11:39  |  Author(s): D. Kowalski

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      ORAL01.06 - S-1 and Cisplatin versus Docetaxel and Cisplatin in Patients with Untreated Advanced NSCLC: An Randomised, Multicenter, Phase 3 Trial

      11:39 - 11:50  |  Author(s): Y. Shi

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      ORAL01.07 - Discussant for ORAL01.05, ORAL01.06

      11:50 - 12:00  |  Author(s): J. Spicer

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    ORAL 02 - PD1 Axis Immunotherapy 2

    • Type: Oral Session
    • Track: Treatment of Advanced Diseases - NSCLC
    • Presentations: 8
    • Moderators:E.B. Garon
    • Coordinates: 9/07/2015, 10:45 - 12:15, Four Seasons Ballroom F1+F2
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      ORAL02.01 - Phase 3, Randomized Trial (CheckMate 017) of Nivolumab (NIVO) vs Docetaxel in Advanced Squamous (SQ) Cell Non-Small Cell Lung Cancer (NSCLC)

      10:45 - 10:56  |  Author(s): K. Reckamp

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      ORAL02.02 - Safety and Efficacy of Nivolumab in an Ongoing Trial of a PD-L1+/- Patient Population with Metastatic Non-Small Cell Lung Cancer

      10:56 - 11:07  |  Author(s): M. Hussein

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      ORAL02.03 - Longer-Term Follow-Up of a Phase 2 Study (CheckMate 063) of Nivolumab in Patients with Advanced, Refractory Squamous Non-Small Cell Lung Cancer

      11:07 - 11:18  |  Author(s): L. Horn

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      ORAL02.04 - Discussant for ORAL02.01, ORAL02.02, ORAL02.03

      11:18 - 11:28  |  Author(s): S. Peters

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      ORAL02.05 - Safety and Efficacy of First-Line Nivolumab (NIVO; Anti-Programmed Death-1 [PD-1]) and Ipilimumab in Non-Small Cell Lung Cancer (NSCLC)

      11:28 - 11:39  |  Author(s): N.A. Rizvi

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      ORAL02.06 - Evaluation of PD-L1 Expression in Metachronous Tumor Samples and FDG-PET as a Predictive Biomarker in Ph2 Study (FIR) of Atezolizumab (MPDL3280A)

      11:39 - 11:50  |  Author(s): J.E. Chaft

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      ORAL02.07 - Atezolizumab (MPDL3280A) Combined with Platinum-Based Chemotherapy in Non-Small Cell Lung Cancer (NSCLC): A Phase Ib Safety and Efficacy Update

      11:50 - 12:01  |  Author(s): R. Camidge

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      ORAL02.08 - Discussant for ORAL02.05, ORAL02.06, ORAL02.07

      12:01 - 12:11  |  Author(s): G. Goss

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    ORAL 03 - New Kinase Targets

    • Type: Oral Session
    • Track: Treatment of Advanced Diseases - NSCLC
    • Presentations: 8
    • Moderators:F. Blackhall
    • Coordinates: 9/07/2015, 10:45 - 12:15, Mile High Ballroom 4a-4f
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      ORAL03.01 - Anlotinib as 3rd-Line Treatment for Refractory Advanced NSCLC: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial

      10:45 - 10:56  |  Author(s): B. Han

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      ORAL03.02 - Is EGFR Exon20 Mutation a Prognostic/Predictive Biomarker in Our Lung Cancer Patients?

      10:56 - 11:07  |  Author(s): D.S. Joy Philip

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      ORAL03.03 - EGFR Exon 18 Mutations in Lung Cancer: Molecular Predictors of Sensitivity to Afatinib or Neratinib but Not to Other EGFR-TKIs

      11:07 - 11:18  |  Author(s): Y. Kobayashi

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      ORAL03.04 - Discussant for ORAL03.01, ORAL03.02, ORAL03.03

      11:18 - 11:28  |  Author(s): H. West

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      ORAL03.05 - Clinical Outcomes with Pemetrexed-Based Systemic Therapy in RET-Rearranged Lung Cancers

      11:28 - 11:39  |  Author(s): A. Drilon

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      ORAL03.06 - Activity of Crizotinib in MET Amplified NSCLC: Preliminary Results of the AcSé Trial

      11:39 - 11:50  |  Author(s): D. Moro-Sibilot

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      ORAL03.07 - Response to MET Inhibitors in Stage IV Lung Adenocarcinoma Patients with Mutations That Cause MET Exon 14 Skipping

      11:50 - 12:01  |  Author(s): P. Paik

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      ORAL03.08 - Discussant for ORAL03.05, ORAL03.06, ORAL03.07

      12:01 - 12:11  |  Author(s): R. Salgia

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    ORAL 04 - Adjuvant Therapy for Early Stage Lung Cancer

    • Type: Oral Session
    • Track: Treatment of Localized Disease - NSCLC
    • Presentations: 8
    • Moderators:E. Vallieres
    • Coordinates: 9/07/2015, 10:45 - 12:15, 205+207
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      ORAL04.01 - Final Results of Phase III Trial of Adjuvant Chemo-Immunotherapy in Lung Cancer

      10:45 - 10:56  |  Author(s): H. Kimura

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      ORAL04.02 - Research of Vascular Targeted Therapy in the Postoperative Adjuvant Chemotherapy for Lung Cancer

      10:56 - 11:07  |  Author(s): Z. Chen

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      ORAL04.03 - Preliminary Results of the International Tailored Chemotherapy Adjuvant Trial: The ITACA Trial

      11:07 - 11:18  |  Author(s): S. Novello

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      ORAL04.04 - Discussant for ORAL04.01, ORAL04.02, ORAL04.03

      11:18 - 11:28  |  Author(s): H. Borghaei

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      ORAL04.05 - Results Ph III Trial Customized Adjuvant CT after Resection of NSCLC with Lymph Node Metastases SCAT: A Spanish Lung Cancer Group Trial

      11:28 - 11:39  |  Author(s): B. Massuti

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      ORAL04.06 - Impact of Demographic and Health System Factors on Adjuvant Chemotherapy Use in Stage II Non-Small Cell Lung Carcinoma: A National Cancer Database Analysis from 2000 to 2012

      11:39 - 11:50  |  Author(s): G. Goyal

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      ORAL04.07 - Adjuvant Chemotherapy in Patients with Resected Non-Small-Cell-Lung Cancer Treated with Carboplatin and Oral Vinorelbine - SWITCH I Study

      11:50 - 12:01  |  Author(s): V. Kolek

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      ORAL04.08 - Discussant for ORAL04.05, ORAL04.06, ORAL04.07

      12:01 - 12:11  |  Author(s): G.V.V. Scagliotti

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    ORAL 05 - Surgery

    • Type: Oral Session
    • Track: Treatment of Locoregional Disease – NSCLC
    • Presentations: 9
    • Moderators:P. Van Schil
    • Coordinates: 9/07/2015, 10:45 - 12:15, 201+203
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      Lectureship Award Winner

      10:56 - 11:16

      • Abstract

      No abstract available for this presentation

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      ORAL05.01 - Prognostic Value of 18F-FDG PET/CT in Surgical NSCLC: A Meta-Analysis

      10:45 - 10:56  |  Author(s): J. Liu

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      ORAL05.02 - Quality of Resection in Pathological N2 NSCLC in the Phase 3 Lung Adjuvant Radiotherapy Trial (Lung ART): An Important Factor

      11:16 - 11:27  |  Author(s): P. Thomas

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      ORAL05.03 - Transcervical Mediastinal and Hilar Lymphadenectomy (TCML) Provides Accurate Pre-Treatment Cancer Staging and Facilitates Resection

      11:27 - 11:38  |  Author(s): R.B. Cameron

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      ORAL05.04 - Discussant for ORAL05.01, ORAL05.02, ORAL05.03

      11:38 - 11:48  |  Author(s): I. Opitz

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      ORAL05.05 - Trimodality Therapy in the Treatment of Stage IIIA Non-Small Cell Lung Cancer (NSCLC): A National Cancer Database Analysis

      11:48 - 11:59  |  Author(s): M. Behera

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      ORAL05.06 - Long-Term Survival after Lobectomy for Locally Advanced NSCLC between Improved Video-Assisted Thoracoscopic Lobectomy and Thoracotomy

      11:59 - 12:10  |  Author(s): K. Chen

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      ORAL05.07 - Mediastinal Lymphadenectomy Fulfilling NCCN Criteria May Improve the Outcome of Clinical N0-1 and Pathological N2 Non-Small Cell Lung Cancer

      12:10 - 12:21  |  Author(s): N. Wu

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      ORAL05.08 - Discussant for ORAL05.05, ORAL05.06, ORAL05.07

      12:21 - 12:31  |  Author(s): E. Ruffini

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    ORAL 06 - Next Generation Sequencing and Testing Implications

    • Type: Oral Session
    • Track: Biology, Pathology, and Molecular Testing
    • Presentations: 9
    • Moderators:G. De Lima Lopes
    • Coordinates: 9/07/2015, 10:45 - 12:15, Mile High Ballroom 1a-1f
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      Lectureship Award Winner

      10:45 - 11:05

      • Abstract

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      ORAL06.01 - Genomic Characterization of Large-Cell Neuroendocrine Lung Tumors

      11:05 - 11:16  |  Author(s): L. Fernandez-Cuesta

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      ORAL06.02 - Targeted Deep Sequencing of EGFR/KRAS/ALK-Negative Lung Adenocarcinoma Reveals Potential Therapeutic Targets

      11:16 - 11:27  |  Author(s): S.M. Lim

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      ORAL06.03 - Genome-Wide Gene Copy Number Analysis by OncoScanTM FFPE Assay in 976 Resected NSCLC From LACE-Bio2

      11:27 - 11:38  |  Author(s): M.S. Tsao

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      ORAL06.04 - Discussant for ORAL06.01, ORAL06.02, ORAL06.03

      11:38 - 11:48  |  Author(s): R. Govindan

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      ORAL06.05 - Molecular Tumor Board (MTB) in Non-Small Cell Lung Cancers (NSCLC) to Optimize Targeted Therapies: 4 Years' Experience at Gustave Roussy

      11:48 - 11:59  |  Author(s): D. Planchard

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      ORAL06.06 - Impact of Reflex EGFR/ALK Testing on Time-To-Treatment and Integration of Personalized Medicine in Advanced Non-Small Cell Lung Cancer Patients

      11:59 - 12:10  |  Author(s): P.K. Cheema

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      ORAL06.07 - An Integrated Cost-Effectiveness and Outcome Analysis Based on Multiplex Lung Cancer Genotyping in the Network Genomic Medicine

      12:10 - 12:21  |  Author(s): A. Kostenko

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      ORAL06.08 - Discussant for ORAL06.05, ORAL06.06, ORAL06.07

      12:21 - 12:31  |  Author(s): P. Yang

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    ORAL 07 - Lung Cancer Pathogenesis

    • Type: Oral Session
    • Track: Biology, Pathology, and Molecular Testing
    • Presentations: 8
    • Moderators:J. Sage
    • Coordinates: 9/07/2015, 10:45 - 12:15, 102+104+106
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      ORAL07.01 - Evaluation of Epigenetic Mechanisms of Pluripotency in Human Respiratory Epithelia

      10:45 - 10:56  |  Author(s): V. Shukla

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      ORAL07.02 - Metabolic Reprogramming in the Airway Epithelium of Individuals at High Risk for Lung Cancer

      10:56 - 11:07  |  Author(s): S.M.J. Rahman

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      ORAL07.03 - MMP12 and LMO7 Are Key Genes Involved in the Early Pathogenesis of Squamous Cell Carcinoma of the Lung

      11:07 - 11:18  |  Author(s): V.H. Teixeira

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      ORAL07.04 - Discussant for ORAL07.01, ORAL07.02, ORAL07.03

      11:18 - 11:28  |  Author(s): M.B. Beasley

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      ORAL07.05 - Differential Tumorigenic Properties of Mesenchymal Cells From Neoplastic and Non-Neoplastic Human Lung in NSCLC

      11:28 - 11:39  |  Author(s): D. Madeddu

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      ORAL07.06 - Sox2 Cooperates with Lkb1 Loss to Promote Mouse Model of Squamous Cell Lung Cancer

      11:39 - 11:50  |  Author(s): A. Mukhopadhyay

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      ORAL07.07 - Evidence and Mechanism for the Transdifferentiation of Lung Adenocarcinoma to Squamous Cell Carcinoma

      11:50 - 12:01  |  Author(s): H. Ji

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      ORAL07.08 - Discussant for ORAL07.05, ORAL07.06, ORAL07.07

      12:01 - 12:11  |  Author(s): Y. Yatabe

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    ORAL 08 - Smoking Cessation, Tobacco Control and Lung Cancer

    • Type: Oral Session
    • Track: Prevention and Tobacco Control
    • Presentations: 8
    • Moderators:G. Warren
    • Coordinates: 9/07/2015, 10:45 - 12:15, 601+603
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    ORAL 09 - CT Screening - New Data and Risk Assessment

    • Type: Oral Session
    • Track: Screening and Early Detection
    • Presentations: 8
    • Moderators:J. Mulshine
    • Coordinates: 9/07/2015, 10:45 - 12:15, Mile High Ballroom 2a-3b
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      ORAL09.01 - Discerning Malignant and Benign New Nodules at Incidence Rounds of CT Lung Cancer Screening: The Role of Volume and Predicted Volume Doubling Time

      10:45 - 10:56  |  Author(s): J.E. Walter

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      ORAL09.02 - Results of the Fourth Screening Round of the NELSON Lung Cancer Screening Study

      10:56 - 11:07  |  Author(s): U. Yousaf-Khan

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      ORAL09.03 - The Danish Lung Cancer Screening Trial: Results 5 Years after Last CT Screening

      11:07 - 11:18  |  Author(s): J.H. Pedersen

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      ORAL09.04 - Discussant for ORAL09.01, ORAL09.02, ORAL09.03

      11:18 - 11:28  |  Author(s): N. Peled

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      ORAL09.05 - Lung-RADS versus the McWilliams Nodule Malignancy Score for Risk Prediction: Evaluation on the Danish Lung Cancer Screening Trial

      11:28 - 11:39  |  Author(s): S.J. Van Riel

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      ORAL09.06 - The Cancer Risk Management Model: A Tool to Inform Canadian Policymakers Implementing Low-Dose CT Screening for Lung Cancer

      11:50 - 12:01  |  Author(s): W.K. Evans

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      ORAL09.07 - Economic Evidence for the Use of Risk-Selection and Risk-Stratification for Lung Cancer Screening Programs

      11:39 - 11:50  |  Author(s): S. Cressman

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      ORAL09.08 - Discussant for ORAL09.05, ORAL09.06, ORAL09.07

      12:01 - 12:11  |  Author(s): S. Malkoski

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