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Fumihiko Hoshi
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P26 - Mesothelioma, Thymoma and Other Thoracic Malignancies - Thymic Malignancies (ID 218)
- Event: WCLC 2020
- Type: Posters
- Track: Mesothelioma, Thymoma and Other Thoracic Malignancies
- Presentations: 1
- Moderators:
- Coordinates: 1/28/2021, 00:00 - 00:00, ePoster Hall
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P26.08 - Postoperative Course of Thymoma with Myasthenia Gravis. (ID 2888)
00:00 - 00:00 | Presenting Author(s): Fumihiko Hoshi
- Abstract
Introduction
10 to 15% of cases of myasthenia gravis have thymoma. In cases with thymoma, extended thymectomy is performed, and surgery is expected to improve symptoms of myasthenia gravis. However, it often takes a long time to improve symptoms after surgery, and there are many unclear points about the cases leading to the improvement of symptoms. In addition, there are cases in which crisis occurs due to surgical stress, and it is necessary to examine the effectiveness of surgery.
Methods
We selected myasthenia gravis patients who underwent extended thymectomy at the Department of Respiratory Surgery, Sendai Medical Center from 2004 to December 2014 were targeted.
Results
10 cases were selected, 3 were men and the average age was 61.6 years. The histological types of thymoma were type AB: 1 case, B1: 4 cases, B2: 3 cases, and B3: 2 cases. In some cases, postoperative MGFA clinical classification and MG-ADL score were improved compared with preoperative, but the dose of oral medication was increased in almost all cases. In two cases, post-operative crisis occurred immediately after surgery, and other cases developed half ~ one year after surgery. Surgery time tended to longer in cases where crises were seen immediately.
Conclusion
For myasthenia gravis, it was considered difficult to improve the symptoms by surgery alone. It was suggested that surgical stress may be involved in the onset of crisis immediately after surgery.
