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Robert Dziedzic
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P41 - Screening and Early Detection - Lung Cancer Screening Programmes (ID 176)
- Event: WCLC 2020
- Type: Posters
- Track: Screening and Early Detection
- Presentations: 1
- Moderators:
- Coordinates: 1/28/2021, 00:00 - 00:00, ePoster Hall
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P41.03 - Long-Term Results of Screening-Detected Lung Cancer in the Polish Cohort. (ID 3727)
00:00 - 00:00 | Presenting Author(s): Robert Dziedzic
- Abstract
Introduction
In recent years, a reduction in mortality due to lung cancer screening using low-dose computed tomography has been proven. The aim of the study was to evaluate the long-term results of the surgical treatment of patients who participated in two lung cancer screening programs in Northern Poland.
Methods
A cohort of 15,293 patients who participated in 2 single-arm observational studies was evaluated with survival analysis. The first study conducted between January 2009 and April 2011 enrolled 8649 participants aged 50-75 years, with at least 20 pack-years. In the second study, 6644 individuals were evaluated, aged 50-79, with at least 30 pack-years. Participants were screened with low-dose computed tomography on a 64-row scanner in the majority of cases.
Results
The pulmonary carcinoma was diagnosed in 258 people, 1.69% of 15,293 participants. From a group of 235 patients with diagnosed non-small cell lung cancer, 167 people (71%) underwent surgery, including 123 patients at stage 0, IA, and IB of lung cancer. 3- and 5-year survival was 85.9% (95% CI 80.1- 92.2) and 75.9% (95% CI 67.5- 85.2) for all operated non-small cell lung cancer patients and 93.8% (95% CI 89.0- 98.8) and 82.0% (95% CI 73.2- 91.8) for patients in pathological stage 0, IA, and IB.
Conclusion
Low-dose computed tomography lung cancer screening is effective for detecting early-stage neoplasms. Surgical treatment of patients with screening-detected early-stage non-small cell lung cancer allows achieving remarkable long-term survival.