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Hirotsugu Notsuda
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P08 - Early Stage/Localized Disease - Epidemiology (ID 117)
- Event: WCLC 2020
- Type: Posters
- Track: Early Stage/Localized Disease
- Presentations: 1
- Moderators:
- Coordinates: 1/28/2021, 00:00 - 00:00, ePoster Hall
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P08.09 - Optimal Follow Up Care for Patients with P-stage I Non-Small Cell Lung Cancer After Surgical Treatment (ID 2151)
00:00 - 00:00 | Presenting Author(s): Hirotsugu Notsuda
- Abstract
Introduction
The proportion of patients with pathological stage I (p-stage I) non-small cell lung cancer (NSCLC) is increasing in Japan. Surgical resection is the curative treatment that improves survival for these patients. Optimal follow-up care after surgical treatment for NSCLC includes close surveillance for early detection of disease recurrence or second primary lung cancer. NCCN guidelines recommends the history and physical examination (H&P) and chest CT ±contrast every 6 months for 2-3 years, then H&P and a low-dose non-contrast-enhanced chest CT annually for stage I NSCLC. We perform FDG-PET and brain MRI annually on lung cancer patients, in addition to the chest CT. However, there is a paucity of evidence for rational follow-up strategies for patients with p-stage I NSCLC after surgical treatment.
Methods
The population of interest for this study was patients who had underwent with surgical treatment for p-stage I NSCLC and were in follow-up.
Results
145 patients who underwent surgery in our department from January 2014 to December 2017 and confirmed p-stage I NSCLC. Post-operative recurrence was observed in 14 of the 145 patients (9.66%). The histological types were adenocarcinoma / squamous cell carcinoma / adenosquamous cell carcinoma in 9/4/1 cases. The recurrence sites were intrathoracic / bone / brain / liver / extrathoracic lymph nodes in 9/1/3/1/2 cases, respectively. In all cases, the primary tumors were solid nodules and no GGN was present. The median recurrence-free survival time was 993 days. Three of the four patients who died of cancer after recurrence were diagnosed with squamous cell carcinoma. Three cases recurred after the third year after surgical treatment, and one of those died of cancer.
Conclusion
Squamous cell carcinoma and the solid nodule in CT are associated with a poor prognosis in patients with p-stage I NSCLC. The specific follow-up schedule for CT may be needed for such patients even after three years.
