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Zelin Ma
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P02 - Diagnostics and Interventional Pulmonology (ID 110)
- Event: WCLC 2020
- Type: Posters
- Track: Diagnostics and Interventional Pulmonology
- Presentations: 1
- Moderators:
- Coordinates: 1/28/2021, 00:00 - 00:00, ePoster Hall
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P02.09 - Comprehensive Investigation of Resected Benign Lesions Suspected for Lung Cancer: Implications for Avoiding Unnecessary Pulmonary Resection (ID 3583)
00:00 - 00:00 | Presenting Author(s): Zelin Ma
- Abstract
Introduction
This study reviewed patients undergoing pulmonary resection for suspected lung cancer with postoperatively proven benign lesions, aiming to share our experience with resected benign lesions and provide potential implications for avoiding unnecessary pulmonary resection.
Methods
We collected patients who underwent pulmonary resection for radiologically suspected lung cancer from 2010 to 2018 at Department of Thoracic Surgery, Fudan University Shanghai Cancer Center (FUSCC). Radiological features, preoperative follow-up time, preoperative pathology and postoperative pathology of these patients were documented. We classified resected benign lesions based on paraffin section and comprehensively evaluated the treatment strategy performed on benign lesions.
Results
14,702 patients were included in this cohort and 1,227 (8.35%) cases were benign lesions. The respective resected benign lesions proportions for pure GGO nodules, part solid nodules and solid nodules were 5.5%, 3.1% and 11.9%. The resected benign lesions rate for patients with longer preoperative follow-up time was much lower (p<0.001). Among the benign lesions, 14.3% were benign tumors, 26.7% were granulomatous, 29.0% were pneumonia, 17.6% were fibrosis and 12.4% were other types. If we consider that resections for granulomatous and pneumonia radiologically featured as solid nodules exceeding 2cm, benign tumor and inflammatory pseudotumor are necessary, the unnecessary pulmonary resection proportion was 4.48%. Both resected benign lesions proportion and unnecessary pulmonary resection proportion significantly decreased by years. For patients with GGO nodules, the median preoperative follow-up time increased with the time being. Wedge resection was the most common surgery strategy especially for small nodules and the proportion of wedge resection were 69.6% for nodules under 1cm.
Conclusion
The resected benign lesions rate and the unnecessary resection rate were low at our department. For patients with GGO nodules, a period of preoperative follow-up is recommended. For solid nodules with inconclusive diagnosis, limited resection should be first considered to avoid the risk of the cancer progressing.