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Xiaotong Guo



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    P06 - Early Stage/Localized Disease - Multiple Primary Lung Cancer (ID 115)

    • Event: WCLC 2020
    • Type: Posters
    • Track: Early Stage/Localized Disease
    • Presentations: 1
    • Moderators:
    • Coordinates: 1/28/2021, 00:00 - 00:00, ePoster Hall
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      P06.04 - Single-Stage Bilateral Pulmonary Resections by Uniportal Video-Assisted Thoracic Surgery for Multiple Small Nodules (ID 2075)

      00:00 - 00:00  |  Presenting Author(s): Xiaotong Guo

      • Abstract

      Introduction

      With the popularization of high-resolution CT and the increasing awareness of people's health examinations in china, more and more patients with synchronous bilateral multiple nodules can be found, and many patients choose surgery for clinical treatment. Single-stage bilateral pulmonary resections is being accepted by more and more people in recent years, but there were few literatures about the uniportal video-assisted thoracic surgery to treat this kind of disease. We have summarized our hospital's experience in performing such operations in the past two years.

      Methods

      Clincal data of 35 patients underwent simultaneous bilateral pulmonary resection by uniportal video-assisted thoracic surgery (VATS) at our hospital between April 2018 and January 2020 were reviewed retrospectively.

      Results

      Simultaneous bilateral pulmonary resection by uniportal video-assisted thoracic surgery (VATS) was undertaken in 35 patients,the cohort of our patients comprised of 15 males and 20 females,middle-aged and elderly patients account for the vast majority (median age,62 years) . Mean follow-up were 8 months (range,3-22months) .Single-stage lobar-sublobar resection were conducted in 11 patients (31.43%) , bilateral sublobar-sublobar resection were performed in 24 patients (68.57%) . Mean preoperative forced expiratory volume in 1 second (FEV1) was 2487 mL and FEV1 mean forced vital capacity (FVC) was 91.00%. Computerized tomography showed thar most of these lesions were ground glass opacity (GGO) (53.61%,52/97), followed by solid (24/97,24.74%) and mixed GGO (21/97, 21.65%) lesions.The average diameter of these nodules was 11.41 mm (range, 1–38mm). Postoperative histopathologic examination revealed that 55 GGO lesions (75.34%) were lung adenocarcinomas. The most advanced pathologic stage of the primary lung cancer lesion in each patient was classified as IA1 (n=10,28.57%),IA2 (n=9,25.71%),IA3 (n=7,20.00%), IB (n=1,2.86%),IIB (n=1,2.86%) and IIIA (n=1,2.86%) . Postoperative histopathologic diagnoses of these lesions included invasive adenocarcinoma (n=53,54.64%),minimally invasive adenocarcinoma (n=8,8.25%),adenocarcinoma in situ (n=8,8.25%),atypical adenomatous hyperplasia (n=8,5.25%),benign lesions (n=20,20.62%) .Mean duration of surgery and blood lost was 202 minutes (range,116–381 minutes),89 ml (range, 20–300 ml) respectively. And the average time interval for chest tube placement and hospital stay was 5 days (range,3-14 days ) and 9 days (range,5-35 days) . Postoperative complications included pneumonia(7/35,20%),air leak (2/35,5.7%) and atrial fibrillation(2/35,5.71%). Pneumonia was the major postoperative complication,The incidence of pneumonia in lobar-sublobar group was higher than sublobar-sublobar group (P=0.021),but not related with the time of chest drains(P=0.124) and hospital stay(P=0.978). No wound infection and postoperative 30-day mortality.

      Conclusion

      Single-stage bilateral pulmonary resections by uniportal VATS is a feasible and safe procedure , However, lobar-sublobar pulmonary resections for bilateral lesions increased incidence of developing pneumonia.