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Clarissa Mathias



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    P18 - Locoregional and Oligometastatic Disease - Misc. Topics (ID 128)

    • Event: WCLC 2020
    • Type: Posters
    • Track: Locoregional and Oligometastatic Disease
    • Presentations: 1
    • Moderators:
    • Coordinates: 1/28/2021, 00:00 - 00:00, ePoster Hall
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      P18.06 - Retrospective Epidemiological Study of Locally Advanced Non-Small Cell Lung Cancer Patients in Brazil – RELANCE (LACOG 0118) (ID 2892)

      00:00 - 00:00  |  Author(s): Clarissa Mathias

      • Abstract
      • Slides

      Introduction

      Lung cancer represents an important public health problem in Brazil. Despite suboptimal registry, it is estimated that lung cancer accounted for 28,220 new cases in Brazil in 2016. Nonetheless, there is limited data regarding stage distribution, patterns of treatment and outcomes of NSCLC in Brazil. Around 20-35% of NSCLC patients have stage III at diagnosis. Due to its heterogeneous nature, patients can be amenable to different therapeutic strategies such as upfront surgery, chemoradiation, systemic treatment or palliative care only. Importantly, multidisciplinary team discussion and planning of treatment impacts patients’ outcomes. Little information is available on how stage III NSCLC is treated in clinical practice in Brazil. The RELANCE study aims to capture real world data on stage III NSCLC and to identify possible gaps to achieve optimal treatment for this population in Brazil.

      Methods

      LACOG 0118 RELANCE is a large multi-institutional study that will collect information regarding sociodemographic data, diagnostic tests, treatment and outcome of patients diagnosed with locally advanced (clinical stage IIIA, IIIB and IIIC) NSCLC in Brazil in the period of January 2015 to June 2019.

      Socio-demographic characteristics, clinicopathological features, treatment patterns and outcomes will be extracted from medical charts. Disease status and survival data will be collected up to the last date of follow-up June 2021.

      Primary endpoint is to describe overall survival (OS) of locally advanced stage III NSCLC in Brazil. Descriptive analysis of treatments and outcomes are planned. Multivariate analysis will be used in order to identify prognostic factors for survival using the Cox regression. The expected target sample size is 400 patients with locally advanced NSCLC.

      Results

      As of 25th July, 42 patients have been included, all of them within 6 Brazilians sites. Currently, there are 6 sites awaiting regulatory approval to start enrollment. Recruitment is planned to last until December 2020 when the estimated sample size will be achieved.

      Conclusion

      LACOG 0118 RELANCE study is one of the largest patient registry that will evaluate current clinical practice for stage III NSCLC in Brazil. The study will describe potential gaps to optimal treatment and demographic and socioeconomic factors associated with patient outcome.

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    PL02 - Innovation to Bridge Lung Cancer Care Tomorrow (Japanese, Mandarin, Spanish Translation Available) (ID 141)

    • Event: WCLC 2020
    • Type: Plenary
    • Track: N.A.
    • Presentations: 1
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      PL02.01 - Chair (ID 3901)

      07:00 - 09:00  |  Presenting Author(s): Clarissa Mathias

      • Abstract

      Abstract not provided