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Mohamed Rahli
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EP1.12 - Small Cell Lung Cancer/NET (ID 202)
- Event: WCLC 2019
- Type: E-Poster Viewing in the Exhibit Hall
- Track: Small Cell Lung Cancer/NET
- Presentations: 1
- Moderators:
- Coordinates: 9/08/2019, 08:00 - 18:00, Exhibit Hall
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EP1.12-34 - Small Cell Lung Cancer Revealed by Choroidal Metastasis: Case Report (ID 2516)
08:00 - 18:00 | Presenting Author(s): Mohamed Rahli
- Abstract
Background
Ocular metastasis sit preferentially in the choroid, a vascularized membrane located between the sclera and the retina.
Method
Lung cancer is the second cancer provider of ocular metastasis after breast cancer.
Choroidal metastasis are rarely indicative of primary neoplasia and are part of a generalized cancer.
We experienced a 70-year-old man, an ex-smoker (45 packs/year) which showed a decrease in visual acuity of the right eye.Physical examination was remarkable for just a exophtamia. The ophthalmological report revealed a retinal detachment and a choroidal tumor process of the right eyeball.
Result
The chest CT scan showed a central right pulmonary mass measured 80X50X47 mm and associated with three right superior lobar nodular formations and ipsilatetal mediastinal lymphadenopathy.
Using a flexible bronchoscopy, we found a reduction of the superior right lobby caliber by an infiltrated mucous.
The bronchoscopic biopsy was performed, and the tumor was found to be small cell lung cancer, classified T4N3M1 according to The eight IASLC classification.
Conclusion
The patient had benefit of chemiotherapy combining "Cisplatin and Etoposid" with radiotherapy of the right eyeball.
After three curs of chemotherapy and radiotherapy we note a regression of the exophtamia, the radiological control was demand.
The research primary cancer will be done quickly to allow for the therapeutic management.
Chemotherapy and radiotherapy remain the treatment of choice for limited extension and improved patient survival.
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EP1.15 - Thymoma/Other Thoracic Malignancies (ID 205)
- Event: WCLC 2019
- Type: E-Poster Viewing in the Exhibit Hall
- Track: Thymoma/Other Thoracic Malignancies
- Presentations: 1
- Moderators:
- Coordinates: 9/08/2019, 08:00 - 18:00, Exhibit Hall
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EP1.15-16 - Two Case Report of Malignant Tracheal Tumors (ID 2188)
08:00 - 18:00 | Presenting Author(s): Mohamed Rahli
- Abstract
Background
Primary malignant tumors of the trachea are rare and uncommon, they represent less than 0.01% of adult tumors and about 0.2% of respiratory ones. They are malignant 90% of the time, with squamous cell carcinoma being the most frequent (50–66%) followed by adenoid cystic carcinoma (10–15%).
Method
The first case report concerns a 42 years old man with no medical history, that consulted in our unit with cough, wheezing and shortness of breath, the chest computerized tomography (CT) showed a distal tracheal mass with axophytic extension without carinal involvement, the ascertain size was 34 mm × 40 mm. Neither mediastinal lymphadenopathy nor obvious invasion to surrounding structures was noted. During the flexible bronchoscopy, we found tracheal tumor partially blocking. the anatomopathology study of the biopsy reported a squamous carcinoma.
Result
The second report is about a 20 years old female with an allergic rhinitis history, who consulted with a dyspnea and vigorous cough persisting for more than year. During this this period the symptoms were attached to asthma and were treated by an association inhaled corticosteroid-beta 2 sympathomimetic.
The neck and chest CT showed an endotracheal mass of 26 mm diameter originating from the anterior wall, occluding 70% of the trachea. The bronchoscopy confirmed the same analysis and showed an easy bleeding to the touch. The biopsy revealed an adenoid cystic carcinoma.
The Multidisciplinary decision (pulmonologist, thoracic surgeon, oncologist and anesthesiologist) advised for a surgical resection for the two patients.
Conclusion
The first patient underwent surgery with five tracheal rings resection and end-to-end anastomosis after tree neo-adjuvant chemotherapy with modified 5-fluorouracil and cisaliplatin. A chest CT will be done in 3 months and an endoscopic control in 12 months.
The second patient had benefited also from a reaction with end to end anastomosis followed by radiotherapy. After 3 years no tumor recurrence has occurred.
Careful clinical evaluation, tomography and endoscopic examination are essential for the confirmation and staging of primary tracheal tumors. Surgery remains the best treatment to achieve a long-term survival.
