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Soyeoun Lim
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EP1.11 - Screening and Early Detection (ID 201)
- Event: WCLC 2019
- Type: E-Poster Viewing in the Exhibit Hall
- Track: Screening and Early Detection
- Presentations: 1
- Now Available
- Moderators:
- Coordinates: 9/08/2019, 08:00 - 18:00, Exhibit Hall
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EP1.11-16 - Comparison of Three Diagnostic Modalities for Lung Nodules (Now Available) (ID 1397)
08:00 - 18:00 | Author(s): Soyeoun Lim
- Abstract
Background
Lung cancer screening and computed tomography (CT) have increased the detection of lung nodules. However, the diagnosis and selection of diagnostic modality are difficult for small nodules. The objective of this study was to determine the appropriate modality for lung nodule diagnosis.
Method
We reviewed 446 consecutive cases that underwent radial endobronchial ultrasound (EBUS), percutaneous needle aspiration (PCNA), or surgical resection for the diagnosis of lung nodules (≤3cm) from February 2017 to January 2019. The patients underwent contrast-enhanced chest CT in our hospital before each examination. We performed retrospective data collection and analysis.
Result
Radial EBUS was performed in 120 (27%) cases, of which 73 had a proper diagnosis; PCNA was performed in 151 (34%) cases, of which 131 had a proper diagnosis; surgical resection was performed in 175 (39%) cases, of which 172 had a proper diagnosis. We detected malignancy, benign nodules, and atypical cells in 290 (65%), 139 (31%), and 17 (4%) cases, respectively. The mean sizes measured on CT were 20, 19.7, and 12.1 mm in PCNA, radial EBUS, and surgical resection, respectively (p<0.001). The lung lobe with nodules (p=0.762) was not statistically different among the modalities. Radial EBUS was preferred for centrally located nodules (55/120; 45.8%; p<0.001). Surgical resection showed many portions of ground-glass opacity nodules (p<0.001). PCNA was attempted in peripherally located or solid lung nodules (p <0.001). The failure of diagnosis with PCNA, radial EBUS, and surgical resection occurred in 20 (13.2%), 47 (39.2%), and 3 (1.7%) cases, respectively (p <0.001).
Conclusion
Surgical resection is preferable for small lung nodules and ground-glass opacity nodules; PCNA is preferable for peripherally located and solid nodules; radial EBUS is preferable for centrally located nodules. It is important to select the diagnostic modality based on the characteristics of each nodule.
