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Dionisios Spyratos



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    EP1.11 - Screening and Early Detection (ID 201)

    • Event: WCLC 2019
    • Type: E-Poster Viewing in the Exhibit Hall
    • Track: Screening and Early Detection
    • Presentations: 1
    • Now Available
    • Moderators:
    • Coordinates: 9/08/2019, 08:00 - 18:00, Exhibit Hall
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      EP1.11-15 - Lung Cancer Screening Program with Low-Dose CT in Greek Population (Now Available) (ID 2008)

      08:00 - 18:00  |  Author(s): Dionisios Spyratos

      • Abstract
      • Slides

      Background

      The majority of lung cancer patients are at an advanced stage at the time of diagnosis, when curative treatment is no longer feasible. On this basis, we performed screening with low-dose CT in patients with high risk of lung cancer development.

      Method

      From Feb 2015 to Feb 2019, 500 patients were recruited in the study. Patients were screened for lung cancer with low-dose CT according to European Union position statement expert group.

      Result

      Group A consisted of patients <55 years old (25%) including 80% of current smokers (30 ± 5 pack years) and 15% of overweight subjects. Group B consisted of patients >55 years old (75%) including 65% of current smokers (40 ± 8 pack years) and 9% of overweight subjects. Former smokers were divided into three groups, those who quit a) 15 years ago (48%), b) 10 years ago (29%) and c) 5 years ago (23%). Concomitant diseases of the whole population included hypertension (27%), diabetes mellitus (19%), COPD (24%), coronary disease (12%) and prior cancer (1%). Hypertension, diabetes mellitus and COPD were correlated with smoking in the population studied (p<0.05). Findings (nodules > 10mm) were observed in 13% of patients in Group A and in 8% of Group B. One patient in Group A and one patient in Group B were diagnosed with squamous cell carcinoma and adenocarcinoma respectively. After screening, 13% of the whole population started low fat diet whereas 20% of the whole population refused follow up. Interestingly, 80% of the whole screened population agreed for an annual low-dose CT and 21% of this population quit smoking through screening period (p<0.05).

      Conclusion

      Screening with low-dose CT offers a tool for the early detection of lung cancer that can save lives for those at high risk and might significantly improve the low survival rates for this disease. European countries should take into consideration the implementation of lung cancer screening programs as a preventive care strategy. The value of the screening test in lung cancer patients remains to be further elucidated.

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