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Sirachat Vidhayakorn



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    EP1.11 - Screening and Early Detection (ID 201)

    • Event: WCLC 2019
    • Type: E-Poster Viewing in the Exhibit Hall
    • Track: Screening and Early Detection
    • Presentations: 1
    • Now Available
    • Moderators:
    • Coordinates: 9/08/2019, 08:00 - 18:00, Exhibit Hall
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      EP1.11-13 - Lung Cancer Screening Protocol by Using Low Dose Computerized Tomography in Combination with Digital Tomosynthesis: 4 Years Follow Up Results (Now Available) (ID 3004)

      08:00 - 18:00  |  Author(s): Sirachat Vidhayakorn

      • Abstract
      • Slides

      Background

      Annual Low-dose computerized tomography (LDCT) screening for lung cancer is currently a standard protocol recommendation. However, LDCT has limitations in its high rate of false positive results, accumulation of radiation exposure, and relatively high cost. Using LDCT in combination with Digital Tomosynthesis (DT) may be an alternative screening protocol for lung cancer.

      Method

      A lung cancer screening protocol using LDCT yearly alternate with DT in normal LDCT finding and abnormal finding that stable or decreased after annual LDCT for 2 years in solid and part-solid nodule has been performed in 634 former or current heavy smoker since July 2012 at Chulabhorn Hospital, Thailand.

      Result

      At initial screening of LDCT, 196 (30.9%) had normal lung finding and 438 (69.1%) had abnormal finding. During annual follow up, 187 and 156 cases who had initial normal LDCT underwent DT screening on 1st and 3rd year of follow up, and no lung cancer was diagnosed within the 4 years follow up period. Meanwhile, among 271 participants who had stable or decreased lung lesions and underwent DT on 3rd year follow up, 3 lung cancers was diagnosed on 4th year follow up. Two lung cancers were early stage and one was stage 4, which represented as a new solid nodule, new solid component and new endobronchial lesion on LDCT finding, respectively, while DT could not detected the new solid component of part solid nodule.

      Conclusion

      LDCT in combination with DT would be an alternative protocol for lung cancer screening particularly in normal lung lesion.

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