Author of

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  EP1.11 - Screening and Early Detection (ID 201)

  • Event: WCLC 2019
  • Type: E-Poster Viewing in the Exhibit Hall
  • Track: Screening and Early Detection
  • Presentations: 1
  • Now Available
  • Moderators:
  • Coordinates: 9/08/2019, 08:00 - 18:00, Exhibit Hall

  • 32076

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    EP1.11-17 - The Impact of Occupational Exposure on Detection of Extra-Nodular and Extrapulmonary Lesions in LDCT from a Pilot Silesian Study (Now Available) (ID 2606)

    08:00 - 18:00  |  Author(s): Weronika Bulska-Bedkowska
    • Abstract
    • Slides

    Background
    

    Smoking and additional exposure to occupational factors such as coal dust, can cause changes in the lungs and also in other organs.

    Method
    

    We did the comparative analysis of the prevalence and nature of extra-nodular lesions and extra-pulmonary findings seen in low-dose computed tomographies (LDCT) done in 533 participants of the Pilot Silesian Study of Early Lung Cancer Detection. The study cohort consisted of miners (n=59) and people without occupational exposure (n=474). Statistical analysis was performed using Statistica 13.0 PL. Statistical significance was set at a p value below 0.05. Distribution of variables was evaluated by the Shapiro-Wilk test. The two groups were compared with the U Mann-Whitney test in case of non-normal data distribution. Chi-square test was used.

    Result
    

    The value of ‘pack-years’ for miners was statistically higher than for people without occupational exposure (M: 37 v 30, p=0.01 ). Emphysema was more often found in the group of miners ( 44,07 % v 31,50 %, p = 0.05). COPD was also diagnosed more often in people exposed to coal dust than without occupational risk (45,76 % v 32,07 %, p=0.035). Extrapulmonary findings were reported in 86,44 % of miners and 62,45 % of people without occupational exposure (p=0.00027). Degenerative changes in the skeleton, osteoporosis, calcification in vessels were found statistically more frequently in miners.

    Conclusion
    

    Long-term smoking, exposure to coal dust, physical work could contribute to a faster development of COPD and osteoarticular diseases.

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