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María Bartol Sánchez



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    EP1.10 - Prevention and Tobacco Control (ID 200)

    • Event: WCLC 2019
    • Type: E-Poster Viewing in the Exhibit Hall
    • Track: Prevention and Tobacco Control
    • Presentations: 1
    • Now Available
    • Moderators:
    • Coordinates: 9/08/2019, 08:00 - 18:00, Exhibit Hall
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      EP1.10-04 - Characteristics of Smoker Patients with Lung Cancer in the Lung Cancer (Now Available) (ID 2359)

      08:00 - 18:00  |  Author(s): María Bartol Sánchez

      • Abstract
      • Slides

      Background

      It is already known that tobacco has hamrful effects, however in Spain there is a significant population of smokers. Our aim is to study the characteristics of a sample of smokers and former smokers with lung cancer, evaluated in the Lung Cancer Unit (LCU).

      Method

      Retrospective study with prospective data. All patients were included according to their smoking history in the LCU between 2010-2017. Variables, such as age, sex, histopathology, pack-year index (PYI), COPD, pulmonary emphysema, Charlson index, TNM, death and survival in months were included. Statistical analysis by statistical program SPSS 20.0.

      Result

      We studied 108 smoker patients with an average age of 69.78 ± 10.738, 81.5% men and 18.5% women, 24.1% with COPD, and 42.6% with emphysema. The most frequent histopathologic finding was of adenocarcinoma (ADC) with 34.3%, followed by squamous carcinoma (SC) with 21.3%. 56.8% of men died with a PYI average of 44.26 ± 26.137, and a median survival of 9.00 months (95% CI 4.77-13.22) compared to 52.4% of women who died with a PYI average of 17.67 ± 16,889 and a median survival of 13.00 months (95% CI 0-34.60).

      The most common histopathology among smokers was ADC followed by SC. The distribution in smokers with PYI <20 was as follows: ADC 42.9% and SC 28.6%; with a PYI between 21 and 40 was ADC 36.7% and SC 23.3%; and in those with PYI> 40, ADC 25.0% and SC 22.7%.

      Similarly, those with a PYI less than 21, (57.1%) died with a median survival of 13.00 months (95% CI 0-30,531), most of them with a Charlson index lower than 3 ( 84.7%) and a TNM stage 3 or 4 (61.6%); with a PYI between 21-40, 50% died with a median survival of 8.00 months (95% CI 4.11-11.88), most with a Charlson index less than 3 (81.4%) and a TNM stage 4 (37.5%); and with a PYI greater than 40, 56.8% died with a median survival of 13.00 months (95% CI 7.17-18.72), most of them with a Charlson index less than 3 ( 80.7%) and a TNM stage 3 (38.4%).

      Conclusion

      The most common lung cancer is ADC in all cases.

      The male population is the most affected with a higher mortality and a lower median survival.

      Mortality is similar in the PYI sections studied, where most had TNM stage ≥ 3, while the survival in these same groups was variable.

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