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Raul Cavo Frigerio
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EP1.06 - Mesothelioma (ID 196)
- Event: WCLC 2019
- Type: E-Poster Viewing in the Exhibit Hall
- Track: Mesothelioma
- Presentations: 1
- Now Available
- Moderators:
- Coordinates: 9/08/2019, 08:00 - 18:00, Exhibit Hall
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EP1.06-10 - Malignant Pleural Mesothelioma Diagnosis: An 18-Year-Old Experience (Now Available) (ID 1886)
08:00 - 18:00 | Author(s): Raul Cavo Frigerio
- Abstract
Background
Malignant pleural mesothelioma (MPM) is a rare malignant tumour derived from the embryonic mesoderm, whose most frequent location is the pleura. It regularly occurs between the ages of 60 and 80, and it is strongly related to an asbesto exposure.
This work compiles the joint experience of both the thoracic surgery and the pathological anatomy services of the General Interzonal Hospital for Acute and Chronic Cases “San Juan de Dios” from the city of La Plata, Argentina.
Method
A retrospective analysis was carried out in all the patients with a MPM diagnosis registered in the database of San Juan de Dios Hospital, during the time period from January 2000 to December 2018.
All diagnoses were performed through pleural biopsies, analized by means of a routine haematoxylin-eosin test and confirmed by an immunohistochemistry study (two positive and two negative indicators).
Result
118 cases were analized, and ages ranged from 17 to 89 years (62 years old was the average), 70% were male while 30% female. The biopsy was taken through videothoracoscopy or thoracotomy, except for a case in which Abrams needle was used. In 14% of the cases a second biopsy was necessary to confirm the diagnosis. The histologic patterns were: epithelioid (65%), sarcomatoid (11%), desmoplastic (3%), and biphasic (12%); in 6% of the cases the histologic type was not determined.
Conclusion
We could observe that most cases apply to men elder than 70 years of age and that the most frequent histologic pattern is the epithelioid one. Moreover, we could see that the average size of the useful sample for diagnosis and the one which did not require a new biopsy sample was 0.8 cm.
