Virtual Library

Start Your Search

Yaroslav Kmetyuk



Author of

  • +

    EP1.05 - Interventional Diagnostics/Pulmonology (ID 195)

    • Event: WCLC 2019
    • Type: E-Poster Viewing in the Exhibit Hall
    • Track: Interventional Diagnostics/Pulmonology
    • Presentations: 1
    • Now Available
    • Moderators:
    • Coordinates: 9/08/2019, 08:00 - 18:00, Exhibit Hall
    • +

      EP1.05-06 - Benefits of 18F-FDG PET/CT-Guided Core-Needle Biopsy in Necrotic or Recurrent Chest Tumors (Now Available) (ID 1019)

      08:00 - 18:00  |  Author(s): Yaroslav Kmetyuk

      • Abstract
      • Slides

      Background

      In case when we have deal with necrotic chest masses and recurrent tumors histological verification become challenged. This happens because CT and ultrasound imaging don’t give us enough information about vital and necrotized part of tumor. CT-guided core-needle biopsy give us possibility to take sample from almost any part of tumor but only with information about density of tissure. On the other hand, 18F-FDG PET/CT give us information about tumor vitality. But usually, 18F-FDG PET/CT performs after morphological verification and we don't use PET/Ct benefits for biopsy.

      Method

      We analyzed 6 patients with chest malignancies: 3 with primary mediastinal lymphoma, 1 – recurrent Hodgkin’s lymphoma, 1 – lung cancer and 1 thymoma. All of them had had at least non-diagnostic core-needle biopsy followed by non-diagnostic thoracoscopic biopsy (1 patient) of Chamberlain procedure (1 patient). We performed PET/CT in all the patients to define the viable target area for subsequent core-needle biopsy. One patient had the biopsy immediately after PET/CT scanning, using the CT-part of PET/CT scanner for navigation. In 5 patients the biopsies were taken within 1 week after PET/CT scanning under normal CT-control. The imaging data obtained from CT and PET/CT scanning were analyzed and compared using the axial slices and MPR reconstructions with OsiriX MD software. 14G and 16G needles were used for mediastinal and lung tumors respectively. All procedures were performed under local anesthesia on outpatient basis.

      Result

      We received tissue confirmation in all cases. No complications occurred during or soon after the biopsy.

      Conclusion

      Uptake zone of the radiotracer on 18F-FDG PET/CT image correlates with informative biopsy specimen taken from that part of the tumor. We may recommend performing of 18F-FDG PET/CT prior to the repeated core-needle biopsy to get information on viable and necrotic tumor compounds to define the target areas.

      Only Active Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login or select "Add to Cart" and proceed to checkout.