Virtual Library

Start Your Search

Jun Hyeok Lim



Author of

  • +

    EP1.05 - Interventional Diagnostics/Pulmonology (ID 195)

    • Event: WCLC 2019
    • Type: E-Poster Viewing in the Exhibit Hall
    • Track: Interventional Diagnostics/Pulmonology
    • Presentations: 1
    • Now Available
    • Moderators:
    • Coordinates: 9/08/2019, 08:00 - 18:00, Exhibit Hall
    • +

      EP1.05-05 - The Optimal Sequence of Bronchial Washing and Brushing for Diagnosis of Non-Visible Lung Cancer During Non-Guided Bronchoscopy (Now Available) (ID 2311)

      08:00 - 18:00  |  Author(s): Jun Hyeok Lim

      • Abstract
      • Slides

      Background

      The optimum sequence of obtaining bronchial washing and brushing samples in lung cancer patients with non-visible tumor during conventional bronchoscope is uncertain. Recent advanced diagnostic bronchoscopy use only is feasible in a few institutions and can be expensive. The aim of the study was to investigate the diagnostic yield of washing performed after brushing in patients with non-visible tumor during non-guided flexible bronchoscopy (FB).

      Method

      We performed a retrospective review of prospectively collected data of suspected lung cancer patients who were performed washing after brushing in non-visible tumor during non-guided FB from 2010 to 2015. Total 166 patients with histologically confirmed primary lung cancer were enrolled in the study.

      Result

      The overall diagnostic rate was 52.4 %, and the diagnostic yield of bronchial brushing and washing were 37.3 % and 46.4 %, respectively. We compared the diagnostic yield of brushing with washing using McMemar’s test. Washing had a better diagnostic yield, 46.4 % (77/166) vs. 37.3 % (62/166) (p=0.017, kappa index=0.570). Comparison of intra-individual agreements between the positive cytology of brushing or washing and the final pathologic diagnosis were a concordance rate of 89.6 % and 90.3 %, with a kappa value of 0.791 (p<0.001) and 0.801 (p<0.001), respectively. The presence of a bronchus sign, tumor size, and higher standardized uptake value on positron emission tomography scan were predictors of a higher diagnostic yield.

      Conclusion

      In institutions where advanced diagnostic bronchoscopy is unavailable, the sequence of washing after brushing in the diagnosis of non-visible lung cancer during non-guided FB may help improving the diagnostic yield.

      Only Active Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login or select "Add to Cart" and proceed to checkout.