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Rachid Marouf



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    EP1.05 - Interventional Diagnostics/Pulmonology (ID 195)

    • Event: WCLC 2019
    • Type: E-Poster Viewing in the Exhibit Hall
    • Track: Interventional Diagnostics/Pulmonology
    • Presentations: 1
    • Now Available
    • Moderators:
    • Coordinates: 9/08/2019, 08:00 - 18:00, Exhibit Hall
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      EP1.05-04 - Results After Retrospective Study About Coexitence Between Bronchial Carcinoma and Active Tuberculosis in Endemic Aera (Now Available) (ID 1015)

      08:00 - 18:00  |  Author(s): Rachid Marouf

      • Abstract
      • Slides

      Background

      Morocco is an endemic country of tuberculosis (TB); the coexistence of active pulmonary tuberculosis in patients with lung cancer is not uncommon and may delay the management of bronchial carcinoma. To clarify the features and risk factors of cases with coexistence cancer and active TB, the aim of this study is to evaluate the clinical and radiological features through a retrospective study of cases with establishment of a diagnostic score to overcome conflict situation.

      Method

      The medical records of 70 cases between 2008 and 2018 in which lung cancer and active pulmonary tuberculosis are intermingled in the same lobe of the lung were collected using our hospital database. We evaluated demographic data, the ways diagnosis of TB cases, the location of TB and cancer using the serial chest radiographs available for all patients; results of bronchoscopy with sampling for mycobacterial culture were reviewed. The CT findings; size, shape, border and location of the lesions and the possible causes of delay in the diagnosis of lung cancer were analyzed.

      Result

      The findings of 70 patients (62 males and 08 females, aged 36-82 years), there are 47 smokers versus 23 never-smokers, in whom pulmonary TB and bronchogenic carcinoma coexisted in the same lobe were analyzed. Fifteen patients had history of tuberculosis. Isolated upper lung field were involved in 75 % patients. Sixty five per cent of cases had respiratory infection symptoms with presence of air-fluid levels in the affected lung with cavitation. Bronchoalveolar lavage (BAL) was performed with the positivity of smears and cultures in all patients. With regards to chest X-ray features, smokers presented with more advanced, and cavitating lung lesions. The average delay in diagnosing lung cancer was 12 (range, 6-18) months, and the causes of this were misinterpretation of lung cancer as active tuberculosis with cavitation in 92% of cases.

      Conclusion

      Pulmonary TB and lung cancer may mimic each other especially in the aspect of the clinical and radiological features. We mainly discussed the diagnostic points to detect the coexistence of lung cancer and pulmonary tuberculosis at early stage.

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