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David Boulate



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    P2.17 - Treatment of Early Stage/Localized Disease (ID 189)

    • Event: WCLC 2019
    • Type: Poster Viewing in the Exhibit Hall
    • Track: Treatment of Early Stage/Localized Disease
    • Presentations: 1
    • Moderators:
    • Coordinates: 9/09/2019, 10:15 - 18:15, Exhibit Hall
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      P2.17-24 - Minimally Invasive Surgery for Lung Cancer Improves Short Term Outcomes in Patients with History of Head and Neck Carcinoma (ID 2309)

      10:15 - 18:15  |  Presenting Author(s): David Boulate

      • Abstract

      Background

      Lung cancer resections are at high risk for major complications in patients with history of head and neck carcinoma (HNC). We initiated a minimally invasive video assisted thoracic surgery (VATS) program since 2014. Our objective was to determine whether VATS lobectomy had better short term outcome than open lobectomy in this subset of patients.

      Method

      We performed a retrospective monocentric analysis of consecutive standard lobectomies performed for lung cancer in patients with history of HNC at our institution between January 2010 and December 2017. Patients with more complex procedures were excluded. Patients’ characteristics and short term outcome were compared between VATS and open lobectomy (OL) groups. Quantitative data were compared using parametric test when normally distributed and using non-parametric test when not normally distributed. Qualitative data were compared using Chi2 or exact Fischer’s test when appropriate. P<0.05 was considered significant.

      Result

      Among 85 patients, 52 underwent an OL and 33 VATS lobectomy. There was no significant difference between the two groups regarding age, sex ratio, HNC location, history of HNC treatment, pathology and stage of lung cancer, history of coronary artery disease, respiratory function or neutrophil to lymphocyte ratio. Postoperative death occurred in 2 patients only in the OL group. In the VATS group, there was a significant decrease in proportion of postoperative life-threatening complications requiring hospitalization in intensive care unit (12/52 vs. 1/33, P=0.01). The main results are reported in the Table.

      table abstract iaslc 2019.jpg

      Conclusion

      We found that minimally invasive thoracic surgery was associated with better short term outcomes compared to open surgery for lung cancer resection in patients with history of HNC. Therefore, we suggest that standard lobectomy in patients with history of HNC should be performed by VATS procedure. Further studies are required to confirm our finding.