Author of

• 31680

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  P2.16 - Treatment in the Real World - Support, Survivorship, Systems Research (ID 187)

  • Event: WCLC 2019
  • Type: Poster Viewing in the Exhibit Hall
  • Track: Treatment in the Real World - Support, Survivorship, Systems Research
  • Presentations: 1
  • Moderators:
  • Coordinates: 9/09/2019, 10:15 - 18:15, Exhibit Hall

  • 31683

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    P2.16-03 - IELCART Quality of Life in the First Year After Surgery for Stage IA Lung Cancer Patients: Preliminary Results (ID 1409)

    10:15 - 18:15  |  Author(s): Rebecca M Schwartz
    • Abstract

    Background
    

    To compare quality of life (QoL) after lobectomy (L) and sublobar resection (SLR) within the first postoperative year among patients undergoing video-assisted thoracoscopic surgery.

    Method
    

    We used a prospective cohort of Stage I lung cancer patients from the Initiative for Early Lung Cancer Research on Treatment (IELCART). QoL used three validated instruments: SF-12 physical (PCS) and mental health (MCS), FACT-L lung cancer symptoms, and PHQ-4 for anxiety and depression. The QoL scores were measured before surgery, and within 4, 6, and 12 months after surgery. For each QoL measure, a piece-wise linear mixed effects model was used to estimate changes in average scores and test for differences between L and SLR patients within 2 months post-surgery and from 2 to 12 months. Social support was also assessed at baseline using the MOS survey.

    Result
    

    Of the 160 patients, 58 (36.3%) had L and 102 (63.7%) SLR. After adjustment for demographics, BMI, pack-years of smoking, and comorbidities, mean QoL and social support scores at baseline did not differ between L and SLR patients. The post-operative rates of change are given in Table 1. L showed significant decreases in PCS (p = .01) and anxiety scores (p = .0001) within 2 months post-surgery and significant improvement from 2 to 12 months in PCS (p = .005) and FACT-L QoL scores (p = .01). SLR anxiety scores decreased (p = .004) within the first two months post-surgery; PCS did not change significantly within the first two months but improved significantly (p = .02) from 2 to 12 months. Other measures were stable across the year after surgery. No significant differences between L and SLR were detected in the post-operative rates of change.

    

    Conclusion
    

    Mental health, anxiety, and depression scores either improved or remained stable. Decreases in physical health persisted 2 months postoperatively, but thereafter improved significantly. Implications for intervention include provision of preoperative counseling about anticipated changes in physical function after surgery, and post-op interventions aimed at improving physical function.