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Juan Qi

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    P2.15 - Thymoma/Other Thoracic Malignancies (ID 185)

    • Event: WCLC 2019
    • Type: Poster Viewing in the Exhibit Hall
    • Track: Thymoma/Other Thoracic Malignancies
    • Presentations: 1
    • Moderators:
    • Coordinates: 9/09/2019, 10:15 - 18:15, Exhibit Hall
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      P2.15-01 - Surgical Resection of 61 Cases of Inflammatory Myofibroblastic Tumor of the Lung (ID 1905)

      10:15 - 18:15  |  Author(s): Juan Qi

      • Abstract


      Inflammatory myofibroblastic tumor (IMT) of the lung is rare soft tissue tumor, with low malignant potential. Here we report 61 cases of surgically resected IMT of the lung.


      Surgically resected IMT of the lung, during the period of September 2004 to July 2010 were retrospectively studied. Of the 61 patients, 40 were male (65.6%), 21 female (34.4%); aged 34 to 77 years old (middle age 55). The symptoms included cough in 32 cases (52.5%), bloody sputum 19 (31.1%), sputum 14 (23.0%), fever 13 (21.3%), chest pain 10 (16.4%), hemoptysis 8 (13.1%), shortness of breath 6 (9.8%), shoulder pain 2 (3.2%), sore throat 1 (1.6%), and asymptomatic 9 (14.8%). Chest CT showed 50 cases (81.2%) were round-ball-like pulmonary nodules, most with smooth and clear borders, while speculated 18 (29.5%), lobulated 13 (21.3%), cavity or vacuole sign 12 (19.7%), calcification 7 (11.5%), pleural indentation 6 (9.8%), and vessel convergence 1 (1.6%). Fibrobronchonscopy was performed in 13 cases but no malignant evidence obtained. CT guided fine-needle biopsy was refused by the patients, and surgical resection was requested.


      Wedge resection was performed in 29 cases (47.5%), and lobectomy in 27 cases (44.3%) (lymph node dissection was performed in 6 suspected cases), segmentomy 5 cases (8.2%). Frozen pathological diagnosis were performed in 59 cases (96.7%), IMT was diagnosed in 38 cases (64.4%) (with alveolar epithelial dysplasia in 14 cases), inflammation or benign disease in 18 cases (30.5%), granulomatous inflammation in 2 cases (3.4%), and malignant in 1 case (1.7%). All patients recovered smoothly except one case received second thoracotomy on the day of surgery due to postoperative hemothorax; no other serious complications happened; all cases were discharged on about the 10th day postoperatively as usual. IMT was confirmed in all these 61 surgical resected cases by the postoperative pathological diagnosis. Follow-up showed all patients recovered well, and no recurrence and metastasis found.


      IMT of the lung has no specific symptoms, lacks specific CT imaging characteristic to distinguish from lung cancer. Surgical resection is of first choice for treatment of IMT of the lung, with no recurrence and metastasis found; wedge resection is recommended; lobectomy and lymph node dissection may be reasonable and necessary for certain suspected cases. Surgical resected IMT of the lung has a good prognosis according to our limited cases and short-time observations. (This study was partly supported by Science Foundation of Shenyang City, China, No. F16-206-9-05, 17-230-9-71)