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P2.11 - Screening and Early Detection (ID 178)
- Event: WCLC 2019
- Type: Poster Viewing in the Exhibit Hall
- Track: Screening and Early Detection
- Presentations: 1
- Now Available
- Coordinates: 9/09/2019, 10:15 - 18:15, Exhibit Hall
P2.11-26 - Survival of Patients with Multiple Primaries and Single Lung Cancer - A Comparative Analysis (Now Available) (ID 354)
10:15 - 18:15 | Author(s): Jerzy Romaszko
From the mid-1980s, lung cancer is the most commonly diagnosed malignant tumor. Longer survival is associated with an increased likelihood of new, subsequent neoplasms. The incidence of multiple primary neoplasms in the oncology population ranges from 0.73 to 11.7%. The aim of the study was to assess the survival of patients with single lung cancer in relation to patients with multiple primary neoplasms.Method
The study was conducted based on the retrospective analysis of data collected from patients hospitalized at the Center for Pulmonary Diseases in Olsztyn (Poland). Data on multiple malignancies (140 patients) were collected from January 2013 to December 2017. Data on single primaries (601 patients) were collected from January 2016 to December 2017. Total survival was calculated beginning from the date of the first cancer diagnosis to the day of death or last observation. The statistical analysis was conducted using Statistica version 12.Result
Based on the collected data, it was revealed that the survival of patients with a single lung cancer (0.17 years; SD 0.81) is significantly shorter than those who had multiple primaries (7.15 years; SD 7.42) (p <0.05). The average survival time of cancer patients with metachronous tumors (8,29 years; SD: 7.58) is significantly longer than patients with synchronous tumors (1.30 years; SD: 1.17) (p <0.05) and single ones (0.71 SD: 0.82) (p<0.05). It was also revealed that patients who smoked in a group of single cancer lived shorter than those with multiple malignancies (p<0.05). The average number of packyears for patients with multiple tumors was 33.95 (SD: 24.95), and with single primaries 39.90 (SD: 21.26).Conclusion
Survival time for patients with single lung cancer is worse than for patients with multiple tumors, both in relation to the first and subsequent tumors. Smoking reduces survival time of patients with both multiple and single primaries.
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