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Joon Chang
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P2.05 - Interventional Diagnostic/Pulmonology (ID 168)
- Event: WCLC 2019
- Type: Poster Viewing in the Exhibit Hall
- Track: Interventional Diagnostics/Pulmonology
- Presentations: 1
- Moderators:
- Coordinates: 9/09/2019, 10:15 - 18:15, Exhibit Hall
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P2.05-16 - Diagnostic Value of Concomitant Use of Radial Probe Endobronchial Ultrasound with Guide Sheath and Transbronchial Biopsy in Lung Cancer (ID 313)
10:15 - 18:15 | Author(s): Joon Chang
- Abstract
Background
Although using radial endobronchial ultrasound with guide sheath (r-EBUS-GS) has shown its diagnostic power in peripheral pulmonary lesion, its actual utility is still low due to variable diagnostic performance. To overcome its limitation, we evaluated the feasibility and efficacy of r-EBUS-GS when combined with transbronchial biopsy (TBB).
Method
We retrospectively reviewed the medical records of 74 patients with NSCLC who underwent r-EBUS-GS plus TBB or TBB alone as diagnostic methods between 2017 Aug. and 2018 Nov. at the Severance hospital. Subjects were grouped by diagnostic modalities used (r-EBUS-GS plus TBB vs. TBB alone). Each group was matched by age, sex, biopsy location. Chi-square analysis and paired-t test were used to compare the characteristics, and to find the factors which affect to the diagnostic yield.
Result
In each group, the number of male subjects was 21 and their mean age was 67.5 and 67.3, respectively. Lesion size was statistically smaller in r-EBUS-GS group. Although r-EBUS-GS alone (15/37, 40.5%) showed poor diagnostic yield, combination of r-EBUS-GS and TBB (27/37, 72.9%) showed higher than TBB alone group (23/37, 62.1%). Lung lesion with bronchus sign was revealed significant relationship with higher diagnostic yield (p<0.005).
Table 1. Lesion characteristics of each group Lesion characteristics
r-EBUS-GS+TBB
(n=37)
TBB only
(n=37)
P-value
Location
1.000
- RUL
8 (21.6%)
8 (21.6%)
- RML
3 (8.1%)
3 (8.1%)
- RLL
10 (27.0%)
10 (27.0%)
- LUL
11 (29.7%)
11 (29.7%)
- LLL
5 (13.5%)
5 (13.5%)
CT finding
0.193
- Nodule/mass
27 (73.0%)
26 (70.3%)
- Subsolid GGO
9 (24.3%)
6 (16.2%)
- GGO or consolidation
1 (2.7%)
5 (13.5%)
Size
23.6 ± 7.6
34.5 ± 15.5
< 0.001
- < 20
13 (35.1%)
7 (18.9%)
- 20-30
17 (45.9%)
11 (29.7%)
- > 30
7 (18.9%)
19 (51.4%)
Pleural distance
14.8 ± 14.4
10.3 ± 10.5
0.102
ConclusionTable 2. Comparison of diagnostic yield according to biopsy methods Diagnostic yield
r-EBUS-GS+TBB (n=37)
TBB only
(n=37)
r-EBUS-GS only
combined
- Accuracy
15/37 (40.5%)
27/37 (72.9%)
23/37 (62.1%)
Combination of r-EBUS-GS and TBB has higher diagnostic power than using r-EBUS-GS or TBB alone.
