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Chan Kwon Park
EP1.01 - Advanced NSCLC (ID 150)
- Event: WCLC 2019
- Type: E-Poster Viewing in the Exhibit Hall
- Track: Advanced NSCLC
- Presentations: 1
- Coordinates: 9/08/2019, 08:00 - 18:00, Exhibit Hall
EP1.01-19 - Updated Statistics of Never-Smoker Female Lung Cancer in Korea (ID 1330)
08:00 - 18:00 | Author(s): Chan Kwon Park
The clinical characteristics and prognostic factors of patients with lung cancer are expected to differ with respect to geographical differences from the past to the future. According to epidemiological, clinical and biological characteristics, lung cancer in never-smokers is a different disease from lung cancer in smokers.Method
To investigate the updated statistics of never-smoker female lung cancer in Korea, we analyzed data from the Korean Statistical Information Service and the Korea Central Cancer Registry in 2014.Result
According to the Korean Statistical Information Service, lung cancer deaths in the Korean population have been increasing in both men and women since the early 1980s. Among the total of 17,980 deaths due to lung cancer in 2017, men accounted for 13,272 and women accounted for 4,708. Of a total of 25,780 incidences of lung cancer in 2016, men accounted for 17,790 and women accounted for 7,990. Considering that the lung cancer incidence in Korean women was 3,592 in 2000, it increased by more than 2-fold in 16 years. However, after age-standardized adjustment, the lung cancer incidence has recently been stable in women. The smoking rate in Korean women was 6.0% in 2017, which has remained stable since 1998. The passive smoking rate in non-smoking women was 6.3% in 2017, which has been decreasing since 2005.
Among the total of 6,460 Korean female patients with lung cancer in 2014, 745 patients were investigated from the Korea Central Cancer Registry. Most Korean women who developed lung cancer were never-smokers (87.5%). According to smoking status, female lung cancer characteristics such as symptoms, stage, histopathology, EGFR mutation positivity, and initial treatment modality were significantly different. Never-smoker female patients with lung cancer showed an increase in asymptomatic disease, stage I lung cancer, histology of adenocarcinoma, EGFR mutation positivity, and curative resection compared to ever-smoker female patients.Conclusion
The trends in epidemiology and clinical characteristics of lung cancer in Korea have changed over time. The never-smoker lung cancer incidence was estimated to increase in Korea. The reason for the stable incidence after the age adjustment could be growth in the Korean elderly population. Further research is needed to guide patient management, as well as future therapeutic strategies for lung cancer.
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