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Fangfang Xie



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    OA01 - Advanced Diagnostic Approaches for Intrathoracic Lymph Nodes and Peripheral Lung Tumors (ID 117)

    • Event: WCLC 2019
    • Type: Oral Session
    • Track: Interventional Diagnostics/Pulmonology
    • Presentations: 1
    • Now Available
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      OA01.07 - Ultrathin Bronchoscopy Combined with VBN and EBUS for the Diagnosis of PPLs With or Without Fluoroscopy: A Randomized Trial (Now Available) (ID 2242)

      10:30 - 12:00  |  Author(s): Fangfang Xie

      • Abstract
      • Presentation
      • Slides

      Background

      Since the utility of low‑dose computed tomography screening for lung cancer, the detection rate of ground‑glass nodules (GGNs) has increased.Transbronchial biopsy for peripheral pulmonary lesions is generally performed using ultrathin bronchoscopy combined with virtual bronchoscopic navigation (VBN) and endobronchial ultrasound (EBUS). The use of fluoroscopy with this method has not yet been explored. The study was designed as a randomized trial to determine the role of fluoroscopy in this method.

      Method

      Patients with peripheral pulmonary lesions suspicious for malignant were enrolled in the study and randomized to two groups, fluoroscopy group and non-fluoroscopy group. Fluoroscopy group was performed with a 3.0 mm external diameter and 1.7 mm internal diameter ultrathin bronchoscope, EBUS, VBN guidance and fluoroscopy. Non-fluoroscopy group was performed with the same ultrathin bronchoscopy combined with EBUS and VBN guidance, but without fluoroscopy. Biopsies Cytological and histological examinations were performed in both groups.

      Result

      A total of 126 patients were enrolled and randomized, of whom 120 patients (60, non-fluoroscopy group; 60, fluoroscopy group) were analyzed. The diagnostic yield was 75% (14 benign and 46 malignant lesions) in the non-fluoroscopy group and 83.3% (6 benign and 54 malignant lesions) in the fluoroscopy group (P=0.37). There were no obvious complications including pneumothorax, bleeding, chest pain and pneumonia in both groups.

      Conclusion

      There was no difference in the diagnostic yield of the non-fluoroscopy group method compared to the FG method using ultrathin bronchoscopy, navigational technology and EBUS for transbronchial biopsy to diagnose peripheral pulmonary lesions.

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