Virtual Library

Start Your Search

Dario SANCHEZ Sanchez Cabrero

Author of

  • +

    Lunch & Poster Display session (ID 58)

    • Event: ELCC 2019
    • Type: Poster Display session
    • Track:
    • Presentations: 1
    • Moderators:
    • Coordinates: 4/11/2019, 12:30 - 13:00, Hall 1
    • +

      203P - Retrospective study about lung carcinoid: Our experience in a Spanish hospital (ID 471)

      12:30 - 13:00  |  Presenting Author(s): Dario SANCHEZ Sanchez Cabrero

      • Abstract
      • Slides


      Pulmonary carcinoids are a very rare group of neoplasia. Typical are the most frequent ones, with earlier onset than atypical carcinoids. There is no clear relationship with smoke. Most are indolent and carcinoid syndrome is rare. In the localized disease, surgery is the best choice. In locally advanced disease, radical radiotherapy can be considered. For the metastatic disease, systemic treatment with somatostatin analogs, multi-kinase inhibitors or chemotherapy can be proposed.

      a9ded1e5ce5d75814730bb4caaf49419 Methods

      We conducted a descriptive and retrospective study including all patients diagnosed with pulmonary carcinoid tumor between January 2013 and January 2018 were included (both localized and metastatic). Other neuroendocrine tumors of the lung were excluded. A Kaplan Meier survival analysis was carried out for each variable to study the overall survival.

      20c51b5f4e9aeb5334c90ff072e6f928 Results

      Of the 42 patients included in the study, most were women (55% vs 45%) and were diagnosed in early stages (83%). Only 14% debuted with metastatic involvement. The main location was the right lung (60%). In 42%, the smoking status is known. Of them, 19% were smokers and 24%, ex-smokers (19% never smoked). 80.5% were diagnosed by cytology (88% as typical and 7.1% as atypical). 12% presented synchronous lung cancer (mostly adenocarcinoma). Localized disease was treated by surgery, mainly by lobectomy (54%). Stage IV patients (66.6%) received systemic treatment with analogs. At the time of the study, 92.7% were still alive (7.3% had died). There were significant differences between tumor stages (p < 0.05) to survival. Even so, there wereńt differences related to age, smoking status or type of surgery.

      fd69c5cf902969e6fb71d043085ddee6 Conclusions

      Most of these tumors exhibit a non-aggressive behavior. According to the previous bibliography, the vast majority are diagnosed in early stages. Radical surgery remains as the gold standard. Experienced centers, can use cytology as a diagnostic method, with less morbidity than biopsy. We didńt found a clear association with smoking status, though there was a clear trend towards to the group related to smoke. According to the literature, overall survival of these patients is long and mainly related to the tumor stage (survival at 2 years is > 85%). More studies will be needed to be able to clarify the prognostic impact of factors.

      b651e8a99c4375feb982b7c2cad376e9 Legal entity responsible for the study

      Hospital Universitario la Paz - Servicio de Oncología Médica.

      213f68309caaa4ccc14d5f99789640ad Funding

      Has not received any funding.

      682889d0a1d3b50267a69346a750433d Disclosure

      All authors have declared no conflicts of interest.


      Only Active Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login or select "Add to Cart" and proceed to checkout.