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Laura Puntí



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    Lunch & Poster Display session (ID 58)

    • Event: ELCC 2019
    • Type: Poster Display session
    • Track:
    • Presentations: 1
    • Moderators:
    • Coordinates: 4/11/2019, 12:30 - 13:00, Hall 1
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      175P - Permanent pleural catheter (PPC) for malignant pleural effusion (PE) in advanced non-small cell lung cancer (NSCLC) (ID 215)

      12:30 - 13:00  |  Author(s): Laura Puntí

      • Abstract
      • Slides

      Background

      Pleural effusion (PE) is a relatively frequent complication in patients (p) with advanced NSCLC that causes refractory symptoms such as pain and dyspnea. These patients frequently need repeated thoracocentesis to relieve symptoms.

      a9ded1e5ce5d75814730bb4caaf49419 Methods

      From May 2008 to September 2018, 30 consecutive patients of our hospital with advanced NSCLC who overwent to PPC implantation were retrospectively evaluated. Baseline characteristics, acute and late complications and outcome were retrospectively collected. Overall survival (OS) was calculated from the date of the PPC implantation to the date of death.

      20c51b5f4e9aeb5334c90ff072e6f928 Results

      Thirty patients were evaluated, 20 were male and 10 female. All patients were death at the cut-off date, the 1st October 2018. Median age at PPC implantation was 66y (range: 47-91) and 80% presented ECOG PS 2. Adenocarcinoma was the most frequent histology (22p). Mean hospital stay was 7 days (range 1-28). Mean catheter duration was 60 days (range 3-181). Median OS was 14.3 weeks (IC 95%, range 1.3-59.1). Four patients (13%) suffered an acute complication: 1 pleuro-cutaneus fistula, 1 empyema, 1 hematoma and 1 needed surgical intervention because the catheter guided was at pleural cavity. After hospital discharge, one p presented a complication, with pleural liquid exit pericatheter. Twenty-five p (83%) presented clinical relief and 11p (37%) received chemotherapy after PPC implantation. Citology of pleural liquid was performed in 23p (77%) and resulted positive for malignancy in 14 cases.

      fd69c5cf902969e6fb71d043085ddee6 Conclusions

      PPC implantation is a safe technique that can cause symptomatic relief in most patients with malignant pleural effusion. However, mean catheter duration and survival after PPC implantation are still low. Therefore a better selection of patients is mandatory.

      b651e8a99c4375feb982b7c2cad376e9 Legal entity responsible for the study

      The authors.

      213f68309caaa4ccc14d5f99789640ad Funding

      Has not received any funding.

      682889d0a1d3b50267a69346a750433d Disclosure

      All authors have declared no conflicts of interest.

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