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Poster Session (ID 8)
- Event: ACLC 2018
- Type: Poster Session
- Presentations: 1
- Coordinates: 11/07/2018, 00:00 - 00:00, Poster Hall
P022 - Association Between Oral Leukoplakia and Lung Cancer: A 28-Year Follow-Up Study in the Linxian General Population Trial (ID 145)
00:00 - 00:00 | Author(s): J. Fan
Oral leukoplakia is a precancerous disorder that is also common among individuals in Linxian. However, the link between oral leukoplakia and risk of lung cancer mortality has not been reported. Therefore we investigated the relationships between oral leukoplakia and lung cancer in the Linxian General Population Trial cohort.
The Linxian General Population Trial cohort, with 29,584 healthy adults enrolled in 1985 and followed through the end of 2012. With collected baseline data, hazard ratios (HR) and 95% confidence intervals (95% CI) for developing lung cancer were estimated using Cox proportional hazard models.
Overall, a total of 29449 were included in the final analysis. During 28 years of follow up, we confirmed a total of 277 incident lung cancer cases. Overall, participants with oral leukoplakia had little risk for developing lung cancer (HR=1.01, 95%CI: 0.67, 1.16). No significant associations were observed for lung cancer in either all subjects or subgroups.
Our results suggest that oral leukoplakia is not associated with increased risk of lung cancer mortality. Future studies are needed to confirm these findings.