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J. Straub

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    Best abstracts selected from submissions 3 (ID 3)

    • Event: ACLC 2018
    • Type: Oral Session
    • Track:
    • Presentations: 1
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      OA06 - Tepotinib in Non-Small Cell Lung Cancer with MET Exon 14-Skipping Mutations or MET Amplification: (ID 140)

      16:20 - 17:00  |  Author(s): J. Straub

      • Abstract

      The MET pathway is frequently deregulated in human cancer, leading to dependency on MET signaling and hence this represents a potential therapeutic target in non-small cell lung cancer (NSCLC). MET alterations include MET exon 14-skipping mutations (METex14+) and MET amplification (METamp); these occur in ~3% and 0.4