Author of

• 25971

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  P3.17 - Treatment of Locoregional Disease - NSCLC (Not CME Accredited Session) (ID 983)

  • Event: WCLC 2018
  • Type: Poster Viewing in the Exhibit Hall
  • Track:
  • Presentations: 1
  • Moderators:
  • Coordinates: 9/26/2018, 12:00 - 13:30, Exhibit Hall

  • 27807

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    P3.17-15 - Therapeutic Outcome of Surgery for Superior Sulcus Tumor (ID 12865)

    12:00 - 13:30  |  Presenting Author(s): Akira Sakurada
    • Abstract
    • Slides

    Background
    

    Treatment of superior sulcus tumor (SST) is challenging and often requires multidisciplinary approach. Accumulation of treatment outcome is a principal issue for the future.

    a9ded1e5ce5d75814730bb4caaf49419 Method
    

    We retrospectively reviewed clinical records of the patients those who were clinically diagnosed to have SST which involved to the 1^st rib but was resectable. From 2000 to 2017, 16 patients were eligible in our hospital. Average age of the patients was 62.3 (40-74). The number of the patients with various properties was following; men 16/ women 3, right lung 5/ left lung 11, squamous cell carcinoma 5/ adenocarcinoma 9/ pleomorphic carcinoma 1, induction chemoradiotherapy 12/ induction chemotherapy 3/ no induction treatment 1, and clinical stage T3N0M0 9/ T3N2M0 2/ T4N0M0 4/ T4N3M0 1. Pathological information and clinical information regarding recurrence and survival were collected. Correlation between prognosis and clinicopathological factors were statistically evaluated by both univariate and multivariate analysis. P value was regarded as statistically significant when it was less than 0.05.

    4c3880bb027f159e801041b1021e88e8 Result
    

    Undertaken surgical approach was posterolateral for 8 cases/ median sternotomy for 6 cases/ transmanubrial approach (TMA) + thoracoscopy for 2 cases. Combined resection extended to the 1^st rib for 6 cases/ 2^nd rib for 4 cases/ parietal pleura for 4 cases/ vessels for 4 cases. For curativity, pathological curative (R0) was achieved in 12 cases, while macroscopic curative (R1) was noted in 4 cases. Effect of induction treatment was revealed as Ef1 for 4 cases/ Ef2 for 7 cases/ Ef3 for 2 cases. There was no death within 30 days after surgery. Morbidity (grade3) occurred in 6. Postoperative recurrence was observed in 8 cases and 7 of them dead from lung cancer. 5-year survival rate was 48.8%. By multivariate analysis, R0 resection was a statistically significant factor which correlates with survival.

    8eea62084ca7e541d918e823422bd82e Conclusion
    

    R0 resection was a critical factor for postoperative survival. Thoracoscopic approach combined with TMA might contribute to reduce surgical invasiveness according to the location of the disease.

    6f8b794f3246b0c1e1780bb4d4d5dc53

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