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  P3.16 - Treatment of Early Stage/Localized Disease (Not CME Accredited Session) (ID 982)

  • Event: WCLC 2018
  • Type: Poster Viewing in the Exhibit Hall
  • Track:
  • Presentations: 1
  • Moderators:
  • Coordinates: 9/26/2018, 12:00 - 13:30, Exhibit Hall

  • 27779

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    P3.16-37 - Comparison of Long-Term Outcomes Between VATS and Open Lobectomies for Stage I NSCLC: Propensity Score-Matching Analysis (ID 12101)

    12:00 - 13:30  |  Presenting Author(s): Risa Oda
    • Abstract
    • Slides

    Background
    

    Video-assisted thoracoscopic surgery (VATS) lobectomy is widely spread for patients with clinical stage I non-small cell lung cancer (NSCLC). The postoperative survival and safety of VATS lobectomy are reported equal or better than those of open lobectomy.

    a9ded1e5ce5d75814730bb4caaf49419 Method
    

    We retrospectively reviewed the clinical data of 186 patients underwent lobectomy with clinical and pathological stage IA NSCLC from January 2008 to December 2013. Perioperative clinical factors and outcomes of patients with clinical and pathological stage IA NSCLC who underwent lobectomy were compared between VATS (n=63) and thoracotomy (n=123) using a propensity score-matching analysis.

    4c3880bb027f159e801041b1021e88e8 Result
    

    In the analysis of 61 matched cases, the VATS group showed decreased blood loss and lower value of the C-reactive protein (CRP) at the peak, despite longer operative time. The VATS group demonstrated a significant longer survival, despite greater number of preoperative comorbidities than the thoracotomy group. The 5-year overall survival (OS) of VATS and thoracotomy were 100% and 89% each (log-rank p=0.02). The 5-year disease-free survival (DFS) of VATS and thoracotomy were 100% and 81% in each (log-rank p<0.01).

    8eea62084ca7e541d918e823422bd82e Conclusion
    

    The results of this study indicate that VATS has some advantages compared with thoracotomy in early stage lung cancer patients.

    6f8b794f3246b0c1e1780bb4d4d5dc53

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