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Kyung Hoon Min

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    P3.15 - Treatment in the Real World - Support, Survivorship, Systems Research (Not CME Accredited Session) (ID 981)

    • Event: WCLC 2018
    • Type: Poster Viewing in the Exhibit Hall
    • Track:
    • Presentations: 1
    • Moderators:
    • Coordinates: 9/26/2018, 12:00 - 13:30, Exhibit Hall
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      P3.15-19 - Risk Factors for Osteoporosis in Lung Cancer Patients (ID 12855)

      12:00 - 13:30  |  Author(s): Kyung Hoon Min

      • Abstract
      • Slides


      Bone related disease is increasingly a problem as lung cancer patients are usually older and the survival rate is increasing. Also cancer patients with multiple chronic comorbidities are at risk of osteoporosis (T-score of ≤ -2.5). The purpose of the study is to investigated the risk factors that attribute to osteoporosis of patients with lung cancer.

      a9ded1e5ce5d75814730bb4caaf49419 Method

      We retrospectively investigated the incidence of osteoporosis of lung cancer patients from March, 2017 to April 2018. A total of 124 patients who were diagnosed with lung cancer at one tertiary academic hospital underwent bone mineral density test.

      4c3880bb027f159e801041b1021e88e8 Result

      Among the 124 patients, 40 (32.3%) showed osteoporosis. Alcohol history, smoking history, lung cancer histology, lung cancer stage, bone metastasis, and comorbidity (hypertension, diabetes, coronary artery disease, cerebrovascular accident, and chronic obstructive pulmonary disease) did not differ significantly among the osteoporosis and normal group . In univariate analysis, age (P = 0.025), BMI (P = 0.028), and female (P < 0.001) were statistically significant. In multivariate logistic regression analysis, age (OR: 1.070, 95% CI:1.016-1.126, p = 0.01), BMI (OR: 0.840, 95% CI:0.738-0.956, p = 0.008), and female (OR: 0.142, 95% CI:0.055-0.366, p < 0.001) were also statistically significant.

      8eea62084ca7e541d918e823422bd82e Conclusion

      One-third of lung cancer patients were diagnosed with osteoporosis at a high rate. Old age, low BMI and female sex were the risk factors affecting osteoporosis of lung cancer patients. Physicians should be aware to of screening bone marrow density of lung cancer patients with old age, low BMI and female group. Studies on the effect of calcium supply and bisphosphonate treatment on bone metastasis and fracture in these osteoporosis patients are underway.


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