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Grace X Ma



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    P1.11 - Screening and Early Detection (Not CME Accredited Session) (ID 943)

    • Event: WCLC 2018
    • Type: Poster Viewing in the Exhibit Hall
    • Track:
    • Presentations: 1
    • Moderators:
    • Coordinates: 9/24/2018, 16:45 - 18:00, Exhibit Hall
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      P1.11-19a - Gender Comparison in Lung Cancer Screening (ID 13069)

      16:45 - 18:00  |  Author(s): Grace X Ma

      • Abstract
      • Slides

      Background

      Persistent underrepresentation of females in lung cancer screening (LCS) trials has raised concerns regarding the accurate perception of differences between the sexes and its generalizability. We examined a balanced cohort of men and women undergoing LCS with the hypothesis that gender does not affect the ability of LCS to successfully detect early-stage lung cancer.

      a9ded1e5ce5d75814730bb4caaf49419 Method

      In an urban, academic medical center, we prospectively collected data on patients referred for LCS from June 2015 to May 2017. We compared age, ethnicity, level of education and smoking history and outcomes of LDCT between men and women. We also measured treatment and complications.

      4c3880bb027f159e801041b1021e88e8 Result

      Two hundred and thirty-six patients underwent LCS. 115 (48.7%) were females and 121 (51.3%) were males. Age did not significantly differ between females (63±5.19) and males (63.93±5.56; p=0.187). There was no gender difference amongst the distribution of ethnicity, education or smoking with 77 (67%) females and 70 (57.9%) males being active smokers (p=0.149). There was a significant difference in the pack years smoked between males (54.8±35.6) and females (43.88±15.54; p=0.024). There was no gender difference in the distribution of LDCT results. 41 (35.7%) females and 56 (46.3%) males diagnosed with Lung-RADs 1, 57 (49.6%) females and 48 (39.7%) males with Lung-RADs 2, 5(4.3%) females and 6 (4.9%) males with Lung-RADs 3 and 8 (6.9%) females and 7 (5.8%) males with Lung-RADs 4 (p=0.542). Three females and 2 males were diagnosed with lung cancer. 4 patients (2 females and 2 males) were treated with surgery and 1 female underwent radiation therapy, all without complications or death.

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      8eea62084ca7e541d918e823422bd82e Conclusion

      Our study of LCS demonstrates the equal participation of men and women. Gender did not impact early detection and successful treatment of lung cancer. This is an opportunity to advocate for enhanced female participation in LCS research to provide meaningful guidance to women and their physicians.

      6f8b794f3246b0c1e1780bb4d4d5dc53

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