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Adrienne Snow



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    P3.11 - Screening and Early Detection (Not CME Accredited Session) (ID 977)

    • Event: WCLC 2018
    • Type: Poster Viewing in the Exhibit Hall
    • Track:
    • Presentations: 1
    • Moderators:
    • Coordinates: 9/26/2018, 12:00 - 13:30, Exhibit Hall
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      P3.11-02 - Lung Cancer Screening in a High Incidence Population: Results of Low-Dose CT Screenings in a Northern Kentucky Community Healthcare System (ID 13918)

      12:00 - 13:30  |  Author(s): Adrienne Snow

      • Abstract
      • Slides

      Background

      The National Lung Screening Trial (NLST) demonstrated that low-dose CT screening increases lung cancer-related survival in at-risk patients. In the U.S., Kentucky has the highest rate of lung cancer, worst historical survival rates and could benefit greatly from a robust screening program. However, concerns have been raised that lung cancer screening performed broadly in the community may not replicate NLST results. Here we evaluate the initial 3 years of a Northern Kentucky community healthcare system lung cancer screening program.

      a9ded1e5ce5d75814730bb4caaf49419 Method

      Medical records related to screening low-dose CTs performed in the St. Elizabeth Healthcare System from January 1, 2015 through February 28, 2018 were retrospectively reviewed. Statistical significance was calculated using a two-sample t-test (p <0.05).

      4c3880bb027f159e801041b1021e88e8 Result

      Overall, 3,496 low-dose CTs were completed. Screenings increased annually, with 218 performed in 2015, 716 in 2016, 1933 in 2017 and 629 through February 2018. Incidences of interventions resulting from screening findings were tallied (Table 1). Screenings produced a shift to an earlier stage at diagnosis (Figure 1).

      Table I

      Number Adverse Events Death
      Total Screens 3496 0 0
      Additional Imaging 428 NM NM
      Diagnostic Procedures 70 4(6%) 0
      Lung Cancers 50(1.4%) NA NA
      Surgical Resections 30 9(30%) 1(3%)
      Chemotherapy and/or Radiation 28 NM NM

      NA-Not Applicable

      NM-Not Measured

      Figure I

      graph.png

      8eea62084ca7e541d918e823422bd82e Conclusion

      The NLST results can be replicated in a community healthcare system with a high incidence of lung cancer.

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