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Christophe Roge



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    P2.10 - Prevention and Tobacco Control (Not CME Accredited Session) (ID 959)

    • Event: WCLC 2018
    • Type: Poster Viewing in the Exhibit Hall
    • Track:
    • Presentations: 1
    • Moderators:
    • Coordinates: 9/25/2018, 16:45 - 18:00, Exhibit Hall
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      P2.10-13 - When Lung Cancer Was Rare: An Historical Study of<br /> Prevalence from 1760 (ID 14174)

      16:45 - 18:00  |  Author(s): Christophe Roge

      • Abstract
      • Slides

      Background

      In 1798 Le Roux, fellow of Bichat, reported that primary lung cancer was nonexistent. Today it is the leading cause of cancer death worldwide with 1.7 million in 2015.

      The aim of this study was to estimate the primary lung cancer prevalence changes around the world
      from the end of the 18th century to 1950, when the first registers became available.

      a9ded1e5ce5d75814730bb4caaf49419 Method

      International autopsic studies results from 1760 to 1950 were collected. All major international
      electronic databases were queried and paper files were obtained when electronic data were not available.

      4c3880bb027f159e801041b1021e88e8 Result

      In 22 countries across America, Europe, Asia, Africa, 1899 references representing 4067041
      autopsies were found. We estimate that, in the first half of the 19th century, lung cancer crude prevalence
      ranged from 1.82*10-5 in France (with a mean age at death of 62.3) to 5.4*10-3 in Germany. This was
      followed by a period of stability in the second part of the 19th century with a prevalence ranging from 0 in
      Italy to 0.16 in UK. These figures increased dramatically from the beginning of the 20th century to reach a
      prevalence of 0.39 in 1947 in Germany.

      8eea62084ca7e541d918e823422bd82e Conclusion

      To our knowledge, it is the first study reporting historical lung cancer prevalence for this
      period: Lung cancer was rare 200 years ago but increased significantly from the beginning of the twentieth
      century onwards, reflecting probably the introduction of manufactured cigarettes.

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