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Anna Doboszyńska



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    P2.10 - Prevention and Tobacco Control (Not CME Accredited Session) (ID 959)

    • Event: WCLC 2018
    • Type: Poster Viewing in the Exhibit Hall
    • Track:
    • Presentations: 1
    • Moderators:
    • Coordinates: 9/25/2018, 16:45 - 18:00, Exhibit Hall
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      P2.10-11 - Impact of Smoking on Multiple Primary Cancers Survival – A Retrospective Analysis (ID 11204)

      16:45 - 18:00  |  Presenting Author(s): Anna Doboszyńska

      • Abstract
      • Slides

      Background

      According to available literature, active tobacco smoking enhances the risks of recurrence and development of new primary malignancies. Smoking also shortens the survival period for patients with a diagnosed neoplastic disease.

      a9ded1e5ce5d75814730bb4caaf49419 Method

      Medical records of 1622 patients hospitalized at the Center for Pulmonary Diseases from January 2013 till March 2017 were retrospectively analyzed, out of which 741 cases with a diagnosis of at least one primary cancer were selected, including 111 patients with multiple primary malignancies. Survival time, the impact of smoking on cancer development and the influence of smoking cessation on the prognosis of the development of new malignancies were analyzed.

      4c3880bb027f159e801041b1021e88e8 Result

      The incidence of multiple primary malignancies in the population of cancer patients amounted to 14.98%. In the group of smokers, those who ceased smoking developed the second primary malignancy later as compared to those who did not: the period between the first and the new cancer was 11.55 years (SD 7.24) for those who quit smoking, whereas for those who continued to smoke after their first cancer diagnosis it was 6.10 years (SD 8.62) (p=0.005). It was revealed that patients who had never smoked lived longer than those who had continued to smoke (p=0.004) and that those who had ceased smoking had a longer survival time than those who had not (p=0.027).figure 1 c&em.jpg

      8eea62084ca7e541d918e823422bd82e Conclusion

      1. The incidence of MPCs in the population of cancer patients amounts to 14.98%. However it is 6.84% in the total study population.

      2. Survival time and the interval between the first and new cancer development are longer for patients who never smoked or ceased smoking as compared to active smokers.

      3. Smoking cessation after the first cancer diagnosis prolongs the period of time before a new cancer is detected, as well as the total survival time for patients since the first cancer diagnosis.

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