Author of

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  P2.01 - Advanced NSCLC (Not CME Accredited Session) (ID 950)

  • Event: WCLC 2018
  • Type: Poster Viewing in the Exhibit Hall
  • Track:
  • Presentations: 1
  • Moderators:
  • Coordinates: 9/25/2018, 16:45 - 18:00, Exhibit Hall

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    P2.01-96 - Dysgeusia Associated with Nutritional and Quality of Life Parameters in Non-Small Cell Lung Cancer Patients Naïve to Chemotherapy (ID 13369)

    16:45 - 18:00  |  Author(s): Karla Paola Sánchez-Lara
    • Abstract
    • Slides

    Background
    

    Dysgeusia (taste alteration) has been reported in more than 50% of patient undergoing chemotherapy, however, it can be present before treatment, and it can be associated with nutritional and quality of life parameters.

    a9ded1e5ce5d75814730bb4caaf49419 Method
    

    We evaluated 65 patients naïve to chemotherapy, the alteration of taste by self-reporting questionnaire and through rinse stimuli to identify detection and recognition thresholds of umami, sweet and bitter taste; as well as, their association with nutritional and quality of life parameters.

    4c3880bb027f159e801041b1021e88e8 Result
    

    Dysgeusia, perceived as a different taste from food was reported in 35% of patients. Those with dysgeusia presents less mean of weight (p=0.059), less lean body mass (p=0.027), higher Fat Mass (p= 0.027), less consumption of protein (0.059), iron (0.022) and sodium (0.034). Patients with dysgeusia reported unfavorable score in functional scales of Health Related Quality of Life (HRQL), than those without dysgeusia; including, Role Functioning (p=0.182*), emotional functioning (p=0.038), cognitive functioning (p=0.017) and social functioning (0.325*). And, the same for symptomatic scales: fatigue (p=0.016), nausea and vomiting (p=0.021), pain (p=0.133*), appetite loss (p<0.001) and constipation (p=0.005).

    

    8eea62084ca7e541d918e823422bd82e Conclusion
    

    Conclusion: Patients with non-small cell lung cancer present dysgeusia before treatment and affect clinical parameters, food consumption habits and quality of life. Nutritional- care must be provided opportunely.

    6f8b794f3246b0c1e1780bb4d4d5dc53

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