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Masafumi Noda



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    P1.05 - Interventional Diagnostics/Pulmonology (Not CME Accredited Session) (ID 937)

    • Event: WCLC 2018
    • Type: Poster Viewing in the Exhibit Hall
    • Track:
    • Presentations: 1
    • Moderators:
    • Coordinates: 9/24/2018, 16:45 - 18:00, Exhibit Hall
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      P1.05-12 - <sup>18</sup>F-FDG PET/CT Findings May Predict Postoperative Acute Exacerbation of Interstitial Pneumonia in Lung Cancer Patients (ID 11131)

      16:45 - 18:00  |  Author(s): Masafumi Noda

      • Abstract
      • Slides

      Background

      Acute exacerbation could be life-threatening for idiopathic interstitial pneumonia (IIP) patients. It is often challenging to choose a surgical treatment for a patient with IIP associated with lung cancer because lung resection is one of the risk factors of acute exacerbation. The objective of this present study was to investigate the correlation between preoperative findings of 18F-FDG PET/CT and postoperative acute exacerbation in patients with IIP associated with lung cancer.

      a9ded1e5ce5d75814730bb4caaf49419 Method

      We retrospectively reviewed the data of 450 patients who underwent lung resection for non-small cell lung cancer between November 2012 and October 2017. We excluded patients who had preoperative radiotherapy (25 patients) from the analysis. All these patients preoperatively underwent 18F-FDG PET/CT for staging lung cancer. The maximum standardized uptake value ( was obtained.world-lc-2018_abst_fig1-tiff.tif

      4c3880bb027f159e801041b1021e88e8 Result

      CT findings of IIPs were found in 31 out of 425 patients (7.1%). Five out of 31 patients (16.1%) developed acute exacerbation after lung resection. These 5 patients had significantly higher SUVmax in the lesions of IIPs compared 26 patients without postoperative acute exacerbation.world-lc-2018_abst_fig2-tiff.tif

      8eea62084ca7e541d918e823422bd82e Conclusion

      This study demonstrated that 18F-FDG PET/CT findings may predict postoperative acute exacerbation of IIP in lung cancer patients.

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    P1.16 - Treatment of Early Stage/Localized Disease (Not CME Accredited Session) (ID 948)

    • Event: WCLC 2018
    • Type: Poster Viewing in the Exhibit Hall
    • Track:
    • Presentations: 1
    • Moderators:
    • Coordinates: 9/24/2018, 16:45 - 18:00, Exhibit Hall
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      P1.16-13 - Photo Dynamic Therapy (PDT) in Our Hospital (ID 12243)

      16:45 - 18:00  |  Author(s): Masafumi Noda

      • Abstract

      Background

      Lung cancer is the leading cause of cancer death worldwide. A large part of lung cancer is diagnosed at an advanced stage, but the number of lung cancer diagnosed at an early stage are increasing due to improved diagnostic imaging techniques. In Japan, sputum cytology for mass screening provides chances to detect very early stage centrally located lung cancer which is good adaptation of PDT.

      Although PDT is less invasive therapy which enable us to treat the patients with poor pulmonary function or poor performance status. It is important to clarify the therapeutic outcome and the morbidity after PDT such as airway narrowing, pneumonia, and sunlight hypersensitivity.

      a9ded1e5ce5d75814730bb4caaf49419 Method

      We analyzed 14 patients who received PDT in Tohoku University Hospital between January 2010 and April 2017 retrospectively and evaluated the therapeutic outcome of PDT.

      4c3880bb027f159e801041b1021e88e8 Result

      14 cases were all male and the average age was 71. Nine cases were detected in cancer screening examinations and other 5 cases were detected accidentally while observing other diseases. Lung cancer existed in trachea 1, in segmental bronchi 4, in sub segmental bronchi 7, and more peripheral lesion 2. All 14 cases were pathologically squamous cell carcinoma. In 2 cases, we performed PDT twice. In 3 cases, we performed surgical resection after PDT. Within follow-up period after PDT, 5 cases developed metachronous lung cancer and were treated with surgical resection or radiation therapy. After these therapies 11 cases alive without recurrence, 1 case alive with recurrence, 1 case died from original disease, and 1 case died from other disease. Only one case suffered airway narrowing after PDT, but other 13 cases had no morbidity.

      8eea62084ca7e541d918e823422bd82e Conclusion

      We concluded PDT is a good treatment in early stage centrally located lung cancer with good outcomes and little morbidity rates.

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