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Akintunde Taiwo Orunmuyi



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    P1.02 - Advocacy (Not CME Accredited Session) (ID 934)

    • Event: WCLC 2018
    • Type: Poster Viewing in the Exhibit Hall
    • Track:
    • Presentations: 1
    • Moderators:
    • Coordinates: 9/24/2018, 16:45 - 18:00, Exhibit Hall
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      P1.02-01 - Imaging of Lung Cancer at the University College Hospital, Ibadan, Nigeria: Does Nuclear Medicine Have Anything to Offer? (ID 14017)

      16:45 - 18:00  |  Author(s): Akintunde Taiwo Orunmuyi

      • Abstract
      • Slides

      Background

      Lung cancer is the most common cause of cancer mortality worldwide. Majority of lung cancer cases occur in less-developed regions. In cancer medicine; bone scintigraphy, a highly sensitive nuclear medicine technique, is often used as a simple whole-body imaging method for metastatic survey. However most recent clinical guidelines on lung cancer management do not recommend the routine use of bone scans to exclude bone metastases, PET/CT (Positron Emission Tomography/Computed Tomography) imaging being the method of choice. In a country where routine PET/CT imaging is not yet available, we investigated bone scan requests in lung cancer patients at our institution since inception of Nuclear Medicine services.

      a9ded1e5ce5d75814730bb4caaf49419 Method

      Bone scan requests over an eleven-year period (2006-2017) at the Nuclear Medicine Centre of the University College Hospital, Ibadan, Nigeria were reviewed. Indications involving lung cancer patients were noted and images as well as reports were reviewed. Standard procedure of planar bone scintigraphy with a gamma camera was employed in all patients following intravenous injection of 15-25mCi 99m Tc- Methylene Diphosphonate (MDP).

      4c3880bb027f159e801041b1021e88e8 Result

      Of over 6,000 patients who had bone scintigraphy during the period under review, only 12 scans (in eleven patients) were done for detection of bone metastases in known lung cancer patients. The mean age was 50.3 years (range 33 – 68) with male to female ratio of 1.2: 1. Histologic sub-type of all but one was non-small cell lung cancer (NSCLC). All of these patients had skeletal related events, primarily severe bone pains requiring radiation therapy/analgesia, while two had known metastases prior to imaging. Bone scan revealed multiple foci of bone metastases in the vast majority (75%) of the cases. Two cases were negative and one equivocal. Only one required additional tomographic (SPECT) imaging to arrive at a conclusive report.

      8eea62084ca7e541d918e823422bd82e Conclusion

      With an average of one bone scan per year and <0.2% of total bone scans in an eleven-year period, bone scintigraphy appears to be underutilized in the setting of lung cancer in our environment. In the absence of PET/CT imaging, bone scintigraphy still has an important role to play in patients’ management and referring physicians are encouraged to embrace this imaging modality.

      6f8b794f3246b0c1e1780bb4d4d5dc53

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