Virtual Library
Start Your Search
N.K. Shukla
Author of
-
+
Poster Display session (Friday) (ID 65)
- Event: ELCC 2018
- Type: Poster Display session
- Track:
- Presentations: 1
- Moderators:
- Coordinates: 4/13/2018, 12:30 - 13:00, Hall 1
-
+
204P - Clinicopathological features, treatment patterns and outcomes of pulmonary metastasectomy (ID 546)
12:30 - 13:00 | Author(s): N.K. Shukla
- Abstract
Background:
Lung is the most common metastatic site, accounting up to 80% of metastases in solid tumors. Although the presence of metastases in patients with malignant tumors is a sign of advanced systemic disease and is considered as non-curative, recent trials have shown survival benefit with pulmonary metastasectomy in selected group of patients. The reason behind some tumors metastasizing exclusively to the lung is unknown. Surgical resection of lung metastasis may significantly impact the long-term outcome in this subset of carefully selected patients. In this study we analyze the results of pulmonary metastasectomy.
Methods:
A prospectively maintained database in the Department of Surgical Oncology, BRA IRCH, AIIMS, New Delhi, India from 1995 to 2017 was accessed and the data of all patients undergoing pulmonary metastasectomy for various primary tumors were analyzed. Clinicopathologic, epidemiological factors, surgical details, post metastasectomy survival and prognostic factors were analyzed.
Results:
A total of 139 patients underwent pulmonary metastasectomy from 1995 to 2017. A total of 195 surgical procedures were carried out for pulmonary metastases, which included surgeries for recurrent metastatic diseases. Patients were predominantly male (M: F = 106:33) and belonged to various age groups ranging from 11years to 68 years (mean = 30 years). Lower limb was the most common site of primary and bone osteosarcoma was the predominant histology of primary tumour (46%), followed by soft tissue sarcomas. Majority of patients underwent open metastasectomy of whom 97% underwent R0 resection. Largest tumor size was 7cms. There were no perioperative mortality. Nineteen patients developed pulmonary recurrence requiring repeat metastasectomy.
Conclusions:
Pulmonary metastasis is a form of systemic failure in many solid tumors. Vast majority end up in palliation. However, in a small subset of patients, pulmonary metastasis are suitable for surgical resection. Pulmonary metastasectomy in combination with or without systemic therapy plays a role in prolonging survival in this subset of patients.
Clinical trial identification:
Legal entity responsible for the study:
All India Institute of Medical Sciences
Funding:
Has not received any funding
Disclosure:
All authors have declared no conflicts of interest.
