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Y. Ahmed



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    Poster Display session (Friday) (ID 65)

    • Event: ELCC 2018
    • Type: Poster Display session
    • Track:
    • Presentations: 1
    • Moderators:
    • Coordinates: 4/13/2018, 12:30 - 13:00, Hall 1
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      89P - The role of palliative care in extensive stage lung cancer (ID 215)

      12:30 - 13:00  |  Presenting Author(s): Y. Ahmed

      • Abstract
      • Slides

      Background:
      Small cell lung cancer (SCLC) represents approximately 10–15% of all lung cancers and is characterized by an aggressive disease course. Despite being a relatively chemotherapy- and radiation- sensitive disease, recurrence and eventual chemoresistance is frequent. prognosis in these patients remains poor, with a median survival of 10–12 months from diagnosis. These patients may experience significant physical and psychological distress throughout the course of their disease, resulting in impaired quality of life (QOL). Early implementation of palliative care can lead to improved symptom control, reduced distress, limit hospitalizations and aid in the decision making with regards to the delivery of care, ultimately providing improved satisfaction with end of life care.

      Methods:
      A retrospective, single-center audit of all patients diagnosed with small cell lung cancer over a six-year period (Jan 2010–Dec 2016). Patients were identified using the Hospitals’ Inpatient Enquiry (HIPE) database. Clinical data were retrieved from hospital pathology and imaging reports as well as patient records. Statistical analysis was performed using a Kaplan-Meier analysis and Pearson correlation coefficient.

      Results:
      115 patients were diagnosed with SCLC. 91/115 patients (79%) were diagnosed with extensive stage disease (40 female patients (44%) and 51 male (56%)). Median age at diagnosis was 66 years. Median ECOG performance status was 1. 63/91 of these patients (69%) received a palliative care review within one month of diagnosis. 51 patients (56%) were alive at six months, with 29 (32%) alive at one year. Patients in the group receiving early palliative care intervention demonstrated improved overall survival, and this correlation was statistically significant (p = 0.01). The median number of hospitalizations in this cohort was also lower (median = 1) than those with delayed palliative care input (median = 2), however, this result was not statistically significant.

      Conclusions:
      Early palliative care input improves quality of life and translates into a survival benefit. Increased awareness of the benefits of palliative care in extensive stage small cell lung cancer at diagnosis is paramount in ensuring optimal patient outcomes and patient satisfaction with their oncological care.

      Clinical trial identification:
      not clinical trial

      Legal entity responsible for the study:
      HSE

      Funding:
      Has not received any funding

      Disclosure:
      The author has declared no conflicts of interest.

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